Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.113916
Description:Burkitt lymphoma receptor 1, GTP-binding protein
Best-Of-UniGene (BOU) SequenceNM_032966
Genomic Coordiantes Displayed:Bases 1286000 to 1296500 of contig Hs11_9491_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.113916.jpeg
Best sense EST/protein match:NM_032966 matched ref|NP_001707.1| (NM_001716) Burkitt lymphoma receptor 1, isoform 1; Burkitt lymphoma (E = 0.0)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  AI676191 cDNA clone IMAGE:2324141 pancreas 3' read Polyadenylation signal
  BF589813 cDNA clone IMAGE:3394188 sciatic nerve 3' read Polyadenylation signal
  AI554183 cDNA clone IMAGE:2208844 uterus 3' read 1.1 kbPolyadenylation signal
  AI678757 cDNA clone IMAGE:2256329 stomach 3' read 1.2 kbPolyadenylation signal
  BG026367 cDNA clone IMAGE:4386537 osteosarcoma, cell line 5' read
  AW338573 cDNA clone IMAGE:2834373 pancreas 3' read Polyadenylation signal
  AI520844 cDNA clone IMAGE:2129876 pancreas 3' read 1.5 kb
  AL353962 cDNA clone DKFZp761M218 amygdala 3' read
  AI445350 cDNA clone IMAGE:2141956 stomach 3' read 1.4 kb
  BE907550 cDNA clone IMAGE:3899407 epithelioid carcinoma 5' read
  BG912356 cDNA clone IMAGE:4940477 anaplastic oligodendroglioma with 1p/19q loss 5' read
  BM044658 cDNA clone IMAGE:5448063 carcinoma, cell line 5' read
  AL353961 cDNA clone DKFZp761M218 amygdala 5' read
  AA369661 cDNA clone ATCC:174258 placenta 5' read
  C17979 cDNA clone GEN555F10 placenta 5' read


  BI909795 cDNA clone IMAGE:5219901 leukocyte 5' read Protein similarity
  BF794688 cDNA clone IMAGE:4339270 lymphoma, cell line 5' read
  AI432809 cDNA clone IMAGE:2121180 lymph 3' read 3.9 kbPolyadenylation signal
  BG236354 cDNA clone IMAGE:4142380 lymphocyte 3' read Polyadenylation signal