Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.134846
Description:BAI1-associated protein 3
Best-Of-UniGene (BOU) SequenceNM_003933
Genomic Coordiantes Displayed:Bases 208000 to 222000 of contig Hs16_10697_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.134846.jpeg
Best sense EST/protein match:BF967425 matched dbj|BAA34454.1| (AB018277) KIAA0734 protein [Homo sapiens] (E = e-109)
Best antisense EST/protein match:BE792494 matched pir||T45061 hypothetical protein c316G12.2 [imported] - human (E = e-100)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BI789155 cDNA clone (no-name) islets of langerhans 3' read Protein similarity
  BI793021 cDNA clone (no-name) islets of langerhans 3' read Protein similarity
  AW733086 cDNA clone IMAGE:2958245 renal cell adenocarcinoma 3' read Protein similarity
  BG339919 cDNA clone IMAGE:4556027 leiomyosarcoma cell line 5' read Protein similarity
  BG338976 cDNA clone IMAGE:4554813 leiomyosarcoma cell line 5' read Protein similarity
  AI086907 cDNA clone IMAGE:1679573 3' read Protein similarity
  BF131571 cDNA clone IMAGE:4044686 hypernephroma 5' read Protein similarity
  AA302073 cDNA clone ATCC:114237 aorta 5' read
  BF688877 cDNA clone IMAGE:4299668 normal pigmented retinal epithelium 3' read Protein similarity
  BI793329 cDNA clone (no-name) islets of langerhans 5' read Protein similarity
  BI962632 cDNA clone (no-name) islets of langerhans 5' read Protein similarity
  BF974746 cDNA clone IMAGE:4336462 primary b-cells from tonsils (cell line) 5' read Protein similarity
  BI160048 cDNA clone IMAGE:5018318 epithelioid carcinoma cell line 5' read Protein similarity
  BG709543 cDNA clone IMAGE:4796101 hypothalamus, cell line 5' read Protein similarity
  BE747038 cDNA clone IMAGE:3929661 adenocarcinoma cell line 5' read Protein similarity
  BE741626 cDNA clone IMAGE:3948876 adenocarcinoma cell line 5' read Protein similarity
  BE792494 cDNA clone IMAGE:3939038 small cell carcinoma 5' read Protein similarity
  AA317548 cDNA clone ATCC:118058 eye 5' read Protein similarity
  BG339128 cDNA clone IMAGE:4554588 leiomyosarcoma cell line 5' read Protein similarity
  BG530555 cDNA clone IMAGE:4697960 embryonal carcinoma 5' read Protein similarity
  BF219262 cDNA clone IMAGE:4095364 glioblastoma 5' read Protein similarity
  BE258153 cDNA clone IMAGE:3355530 retinoblastoma 5' read Protein similarity
  BI597366 cDNA clone IMAGE:5303416 hypothalamus, cell line 5' read Protein similarity
  BG332160 cDNA clone IMAGE:4549940 large cell carcinoma 5' read Protein similarity
  BG500856 cDNA clone IMAGE:4669442 adenocarcinoma 5' read Protein similarity
  BF700642 cDNA clone IMAGE:4285375 primitive neuroectoderm 5' read Protein similarity
  BF207312 cDNA clone IMAGE:4100621 neuroblastoma 5' read Protein similarity
  BF210395 cDNA clone IMAGE:4101306 from chronic myelogenous leukemia 5' read Protein similarity
  BF208356 cDNA clone IMAGE:4092700 carcinoma, cell line 5' read Protein similarity

SENSE ESTs

  BI546056 cDNA clone IMAGE:5259817 hippocampus, cell line 5' read Protein similarity
  AL118986 cDNA clone DKFZp761G05121 amygdala 5' read Protein similarity
  AL120280 cDNA clone DKFZp761L047 amygdala 5' read Protein similarity
  BI831797 cDNA clone IMAGE:5170482 medulla 5' read Protein similarity
  BI755009 cDNA clone IMAGE:5194092 brain 5' read Protein similarity
  F13300 cDNA clone c3ld09 brain Protein similarity
  H18551 cDNA clone IMAGE:51097 brain 5' read 2.1 kbProtein similarity
  T77480 cDNA clone IMAGE:23595 brain 5' read 2.2 kbProtein similarity
  BI771405 cDNA clone IMAGE:5208822 pooled lung and spleen 5' read Protein similarity
  BF967425 cDNA clone IMAGE:4374539 hypothalamus, cell line 5' read Protein similarity
  BG707986 cDNA clone IMAGE:4793904 hypothalamus, cell line 5' read Protein similarity
  AL041517 cDNA clone DKFZp434G2217 testis 5' read Protein similarity
  R61025 cDNA clone IMAGE:42186 brain 5' read 1.3 kbProtein similarity
  BF343436 cDNA clone IMAGE:4150213 glioblastoma with egfr amplification 5' read Protein similarity
  R24790 cDNA clone IMAGE:35437 brain 5' read 1.4 kbProtein similarity
  AA078749 cDNA clone IMAGE:526262 5' read