Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.17805
Description:Homo sapiens cDNA FLJ30997 fis, clone HLUNG1000104
Best-Of-UniGene (BOU) SequenceAK055559
Genomic Coordiantes Displayed:Bases 113162 to 282875 of contig Hs19_11440_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.17805.jpeg
Best sense EST/protein match:No protein match with an e-value of less than 1e-10
Best antisense EST/protein match:BI754970 matched ref|XP_061495.1| (XM_061495) similar to cyclin-box carrying protein (H. sapiens) (E = 5e-18)

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BI754970 cDNA clone IMAGE:5194128 brain 5' read Protein similarity
  BM042307 cDNA clone IMAGE:5557029 melanotic melanoma, cell line 5' read
  BE778499 cDNA clone IMAGE:3867353 retinoblastoma 5' read Protein similarity
  BE742229 cDNA clone IMAGE:3836459 adenocarcinoma cell line 5' read Protein similarity
  BE899305 cDNA clone IMAGE:3952308 adenocarcinoma cell line 5' read
  BI259890 cDNA clone IMAGE:5111078 choriocarcinoma 5' read
  BI755227 cDNA clone IMAGE:5193514 brain 5' read
  AW958844 cDNA clone (no-name)
  BF038869 cDNA clone IMAGE:3865047 adenocarcinoma 5' read
  BE019936 cDNA clone IMAGE:3030090 adenocarcinoma cell line 5' read
  AA357601 cDNA clone ATCC:161952 prostate 5' read
  H05847 cDNA clone IMAGE:43815 brain 5' read 1.9 kb


  BE739087 cDNA clone IMAGE:3826104 hypernephroma 5' read
  BF216503 cDNA clone IMAGE:4103179 glioblastoma 5' read
  BG715180 cDNA clone IMAGE:4798281 hypothalamus, cell line 5' read
  BG499863 cDNA clone IMAGE:4668411 adenocarcinoma 5' read
  BG764037 cDNA clone IMAGE:4862171 melanotic melanoma, high mdr (cell line) 5' read
  BI915811 cDNA clone IMAGE:5247563 brain 5' read
  BG528055 cDNA clone IMAGE:4686224 mucoepidermoid carcinoma 5' read
  BF681568 cDNA clone IMAGE:4296628 prostate 5' read
  BE274196 cDNA clone IMAGE:2967730 melanotic melanoma 5' read
  BG682783 cDNA clone IMAGE:4762003 neuroblastoma, cell line 5' read
  BI964791 cDNA clone (no-name) islets of langerhans 5' read
  BE780373 cDNA clone IMAGE:3871605 retinoblastoma 5' read
  BF212101 cDNA clone IMAGE:4047892 from chronic myelogenous leukemia 5' read
  BF683099 cDNA clone IMAGE:4298023 leiomyosarcoma cell line 5' read
  BG777114 cDNA clone IMAGE:4809679 mucoepidermoid carcinoma 5' read
  BE297662 cDNA clone IMAGE:3530912 rhabdomyosarcoma 5' read
  BG025062 cDNA clone IMAGE:4364256 lymphoma, cell line 5' read
  BE739420 cDNA clone IMAGE:3826104 hypernephroma 3' read
  BI223416 cDNA clone IMAGE:5106169 choriocarcinoma 5' read
  BG683446 cDNA clone IMAGE:4762003 neuroblastoma, cell line 3' read
  BE295170 cDNA clone IMAGE:3530358 rhabdomyosarcoma 5' read
  BE269752 cDNA clone IMAGE:3544567 burkitt lymphoma 5' read
  BE296255 cDNA clone IMAGE:3530359 rhabdomyosarcoma 5' read
  AI129026 cDNA clone IMAGE:1663314 3' read 0.9 kbPolyadenylation signal