Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.20450
Description:BCM-like membrane protein precursor
Best-Of-UniGene (BOU) SequenceNM_020125
Genomic Coordiantes Displayed:Bases 324854 to 364171 of contig Hs1_4563_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.20450.jpeg
Best sense EST/protein match:NM_020125 matched ref|NP_064510.1| (NM_020125) BCM-like membrane protein precursor; B lymphocyte (E = e-141)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BI753917 cDNA clone IMAGE:5193820 brain 5' read
  BI914871 cDNA clone IMAGE:5248078 brain 5' read
  AL134415 cDNA clone DKFZp547F195 brain 5' read
  BI754345 cDNA clone IMAGE:5193717 brain 5' read
  AI929596 cDNA clone IMAGE:2519239 frontal lobe 5' read


  BG236036 cDNA clone IMAGE:4141547 lymphocyte 3' read
  BG230648 cDNA clone IMAGE:4143603 lymphocyte 3' read Polyadenylation signal
  AW664177 cDNA clone IMAGE:2971426 2 pooled high-grade transitional cell tumors 3' read Polyadenylation signal
  AA379112 cDNA clone ATCC:183497 skin 5' read
  AW662401 cDNA clone IMAGE:2973436 colon 3' read Polyadenylation signal
  BE049215 cDNA clone IMAGE:3036226 colon 3' read Polyadenylation signal
  AI682836 cDNA clone IMAGE:2323655 pancreas 3' read 1.8 kbPolyadenylation signal