Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.23450
Description:mitochondrial ribosomal protein S25
Best-Of-UniGene (BOU) SequenceAK024433
Genomic Coordiantes Displayed:Bases 2399062 to 2426324 of contig Hs3_5925_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.23450.jpeg
Best sense EST/protein match:BE889085 matched dbj|BAB15723.1| (AK024433) FLJ00023 protein [Homo sapiens] (E = e-100)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  AL138444 cDNA clone DKFZp434K1029 testis 3' read Polyadenylation signal
  AI986459 cDNA clone IMAGE:2562945 malignant melanoma, metastatic to lymph node 3' read 1.1 kbPolyadenylation signal
  R62456 cDNA clone IMAGE:36675 brain 3' read 1.7 kbPolyadenylation signal
  H05778 cDNA clone IMAGE:43937 brain 3' read 1.7 kbPolyadenylation signal
  AA600370 cDNA clone IMAGE:1069405 kidney 3' read 0.6 kb
  R43874 cDNA clone IMAGE:33604 brain 3' read 1.6 kbPolyadenylation signal
  AV735486 cDNA clone CBLBHH01 cord blood 5' read
  AW873651 cDNA clone IMAGE:3120648 neuroblastoma 3' read Polyadenylation signal
  BI254970 cDNA clone IMAGE:5115090 choriocarcinoma 5' read
  AI926645 cDNA clone IMAGE:2458635 stomach 3' read
  R20724 cDNA clone IMAGE:26141 brain 3' read 1.5 kbPolyadenylation signal
  BF435579 cDNA clone IMAGE:3394964 sciatic nerve 3' read
  AW086104 cDNA clone IMAGE:2590404 brain 3' read
  AW469842 cDNA clone IMAGE:2848312 lymph 3' read
  AW511431 cDNA clone IMAGE:2805964 uterus 3' read
  AI061109 cDNA clone IMAGE:1699784 kidney 3' read
  AW519049 cDNA clone IMAGE:2877010 pancreas 3' read
  AA330632 cDNA clone ATCC:132259 whole embryo 3' read
  Z39217 cDNA clone c14b07 brain 3' read
  AI720236 cDNA clone IMAGE:2335410 colon 3' read
  AW515099 cDNA clone IMAGE:2809071 uterus 3' read
  F01569 cDNA clone c06g12 brain 3' read
  BG496424 cDNA clone IMAGE:4659317 mucoepidermoid carcinoma 5' read
  BG621569 cDNA clone IMAGE:4731063 placenta 5' read
  BE866338 cDNA clone IMAGE:3961366 carcinoma, cell line 5' read
  BF978220 cDNA clone IMAGE:4306961 melanotic melanoma, high mdr 5' read
  BI918895 cDNA clone IMAGE:5245285 brain 5' read
  BF184814 cDNA clone IMAGE:4065230 from chronic myelogenous leukemia 5' read
  BG484195 cDNA clone IMAGE:4618586 lung 5' read
  AA303907 cDNA clone ATCC:115527 aorta 5' read
  BG612017 cDNA clone IMAGE:4739261 adenocarcinoma 5' read
  BG254524 cDNA clone IMAGE:4476612 adenocarcinoma, cell line 5' read
  R12812 cDNA clone IMAGE:26141 brain 5' read 1.5 kb
  BG431238 cDNA clone IMAGE:4613375 kidney 5' read
  H05885 cDNA clone IMAGE:43937 brain 5' read 1.7 kb
  R25712 cDNA clone IMAGE:36675 brain 5' read 1.7 kb
  Z42046 cDNA clone c06g12 brain 5' read
  Z43132 cDNA clone c14b07 brain 5' read
  R19522 cDNA clone IMAGE:33604 brain 5' read 1.6 kb
  BI859942 cDNA clone IMAGE:5394813 mammary adenocarcinoma, cell line 5' read
  BF542066 cDNA clone IMAGE:4067361 hypernephroma 5' read
  AA330633 cDNA clone ATCC:132259 whole embryo 5' read
  BE543896 cDNA clone IMAGE:3457655 choriocarcinoma 5' read
  AA301300 cDNA clone ATCC:191686 testis 5' read
  AA346914 cDNA clone ATCC:148278 heart 5' read
  BG035006 cDNA clone IMAGE:4413547 adenocarcinoma, cell line 5' read Protein similarity
  AL138443 cDNA clone DKFZp434K1029 testis 5' read
  BF211120 cDNA clone IMAGE:4047222 from chronic myelogenous leukemia 5' read
  BF346744 cDNA clone IMAGE:4157040 anaplastic oligodendroglioma with 1p/19q loss 5' read
  AL157600 cDNA clone DKFZp761J0116 amygdala 5' read
  AA356181 cDNA clone ATCC:158326 5' read


  AL597886 cDNA clone DKFZp313H0817 5' read
  BF316772 cDNA clone IMAGE:4136009 neuroblastoma 5' read
  BF314455 cDNA clone IMAGE:4130143 neuroblastoma 5' read
  BM010447 cDNA clone IMAGE:5445070 amelanotic melanoma, cell line 5' read
  BF206324 cDNA clone IMAGE:4100054 neuroblastoma 5' read
  BI254864 cDNA clone IMAGE:5113495 choriocarcinoma 5' read
  AA380629 cDNA clone ATCC:185025 5' read
  BG024082 cDNA clone IMAGE:4394551 duodenal adenocarcinoma, cell line 5' read
  BE799613 cDNA clone IMAGE:3946946 small cell carcinoma 5' read
  BG260417 cDNA clone IMAGE:4479562 transitional cell papilloma, cell line 5' read
  AW249185 cDNA clone IMAGE:2820823 small cell carcinoma 5' read
  BE312324 cDNA clone IMAGE:3502515 neuroblastoma 5' read
  BI822343 cDNA clone IMAGE:5177471 pooled brain, lung, testis 5' read
  BF345789 cDNA clone IMAGE:4153359 anaplastic oligodendroglioma with 1p/19q loss 5' read
  BE791607 cDNA clone IMAGE:3940113 small cell carcinoma 5' read
  BE208522 cDNA clone IMAGE:2823553 small cell carcinoma 5' read
  BI855681 cDNA clone IMAGE:5392059 mammary adenocarcinoma, cell line 5' read
  AA306599 cDNA clone ATCC:160710 5' read
  BM016311 cDNA clone IMAGE:5418837 mammary adenocarcinoma, cell line 5' read
  BG258276 cDNA clone IMAGE:4510681 embryonal carcinoma, cell line 5' read
  BG774780 cDNA clone IMAGE:4811266 choriocarcinoma 5' read
  BE274494 cDNA clone IMAGE:2967154 melanotic melanoma 5' read
  AV709531 cDNA clone ADCAVA04 adrenal gland 5' read
  BE383913 cDNA clone IMAGE:3614271 melanotic melanoma 5' read
  BE277558 cDNA clone IMAGE:3547078 melanotic melanoma 5' read
  BE889085 cDNA clone IMAGE:3915101 leiomyosarcoma 5' read
  BE727061 cDNA clone IMAGE:3833240 melanotic melanoma 5' read
  BE729101 cDNA clone IMAGE:3830677 melanotic melanoma 5' read
  BE727835 cDNA clone IMAGE:3833930 melanotic melanoma 5' read
  BE279536 cDNA clone IMAGE:3504068 choriocarcinoma 5' read
  BI094292 cDNA clone IMAGE:5001427 placenta 5' read
  BG338401 cDNA clone IMAGE:4553878 leiomyosarcoma cell line 5' read
  R57699 cDNA clone F5156 heart 5' read
  AA341570 cDNA clone ATCC:143231 kidney 5' read
  BM129267 cDNA clone (no-name) islets of langerhans 5' read
  BG762438 cDNA clone IMAGE:4859345 melanotic melanoma, high mdr (cell line) 5' read
  BG765051 cDNA clone IMAGE:4863158 melanotic melanoma, high mdr (cell line) 5' read
  AA358256 cDNA clone ATCC:162493 lung 5' read