Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.260238
Description:hypothetical protein FLJ10842
Best-Of-UniGene (BOU) SequenceNM_018238
Genomic Coordiantes Displayed:Bases 171600 to 181400 of contig Hs7_7926_24
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingHs.260238.jpeg
Best sense EST/protein match:AU124538 matched ref|NP_060708.1| (NM_018238) hypothetical protein FLJ10842 [Homo sapiens] (E = e-116)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BG536105 cDNA clone IMAGE:4689117 lung 5' read
  AI800140 cDNA clone IMAGE:2219108 ovary 3' read
  H29787 cDNA clone IMAGE:52966 brain 5' read 1.5 kb
  AI920795 cDNA clone IMAGE:2452305 uterus 3' read 1.4 kb
  R13303 cDNA clone IMAGE:28211 brain 5' read 1.4 kb
  BG506626 cDNA clone IMAGE:4070981 lung 5' read
  AW169453 cDNA clone IMAGE:2658419 uterus 3' read Polyadenylation signal
  H29503 cDNA clone IMAGE:52940 brain 5' read 1.5 kb
  T78749 cDNA clone IMAGE:24174 brain 5' read 1.4 kb
  BG170992 cDNA clone IMAGE:4427372 hypernephroma, cell line 5' read
  AI538012 cDNA clone IMAGE:2189028 stomach 3' read Polyadenylation signal
  AI589262 cDNA clone IMAGE:2222496 pancreas 3' read 1.8 kbPolyadenylation signal
  AA861993 cDNA clone IMAGE:1485668 head and neck 3' read Polyadenylation signal
  R40786 cDNA clone IMAGE:28211 brain 3' read 1.4 kbPolyadenylation signal
  AI968962 cDNA clone IMAGE:2545623 four pooled pituitary adenomas 3' read 2.3 kbPolyadenylation signal
  AA946852 cDNA clone IMAGE:1590024 kidney 3' read 1.0 kbPolyadenylation signal
  H29504 cDNA clone IMAGE:52940 brain 3' read 1.5 kbPolyadenylation signal
  AI358082 cDNA clone IMAGE:1989388 uterus 3' read 3.1 kbPolyadenylation signal
  AI872899 cDNA clone IMAGE:2441454 uterus 3' read 3.0 kbPolyadenylation signal
  AI240698 cDNA clone IMAGE:1848410 pool 3' read 1.1 kbPolyadenylation signal
  AA679593 cDNA clone IMAGE:1128462 kidney 3' read Polyadenylation signal

SENSE ESTs

  AV692263 cDNA clone GKCFRB04 hepatocellular carcinoma 5' read
  AV692283 cDNA clone GKCFRB11 hepatocellular carcinoma 5' read
  AV692260 cDNA clone GKCFRB01 hepatocellular carcinoma 5' read
  R44948 cDNA clone IMAGE:34320 brain 3' read 3.3 kb
  AI002939 cDNA clone IMAGE:1698776 kidney 3' read
  AI686706 cDNA clone IMAGE:2268666 uterus 3' read 3.4 kbPolyadenylation signal
  AA707156 cDNA clone IMAGE:451374 pool 3' read
  BF131526 cDNA clone IMAGE:4044791 hypernephroma 5' read
  BG778116 cDNA clone IMAGE:4806107 adenocarcinoma 5' read
  BM091099 cDNA clone (no-name) fetal pancreas (4 pooled donors, 18 - 20 weeks, stratagene 5' read
  AA074072 cDNA clone IMAGE:531456 3' read Polyadenylation signal
  BF695661 cDNA clone IMAGE:4076228 primitive neuroectoderm 5' read
  BF126313 cDNA clone IMAGE:3934104 liver 5' read
  BG612319 cDNA clone IMAGE:4739003 adenocarcinoma 5' read
  BE566846 cDNA clone IMAGE:3681780 carcinoma, cell line 5' read
  BE258595 cDNA clone IMAGE:3344830 retinoblastoma 5' read
  BF342607 cDNA clone IMAGE:4149395 glioblastoma with egfr amplification 5' read
  BF666992 cDNA clone IMAGE:4278634 primitive neuroectoderm 5' read
  BG248951 cDNA clone IMAGE:4469807 hypernephroma, cell line 5' read
  BF238880 cDNA clone IMAGE:4132464 from chronic myelogenous leukemia 5' read
  BE266316 cDNA clone IMAGE:3536001 small cell carcinoma 5' read Protein similarity
  AU124538 cDNA clone NT2RM4000165 5' read
  BE788808 cDNA clone IMAGE:3878500 large cell carcinoma 5' read
  BI764370 cDNA clone IMAGE:5186372 pooled colon, kidney, stomach 5' read
  BG913988 cDNA clone IMAGE:4942872 anaplastic oligodendroglioma with 1p/19q loss 5' read
  AA703596 cDNA clone IMAGE:450275 pool 3' read
  BG770601 cDNA clone IMAGE:4859409 melanotic melanoma, high mdr (cell line) 5' read
  BI824671 cDNA clone IMAGE:5174790 pooled brain, lung, testis 5' read Protein similarity
  BG768077 cDNA clone IMAGE:4877057 melanotic melanoma, high mdr (cell line) 5' read Protein similarity
  BE899228 cDNA clone IMAGE:3952045 adenocarcinoma cell line 5' read Protein similarity
  BI090177 cDNA clone IMAGE:4998508 placenta 5' read Protein similarity
  BF105045 cDNA clone IMAGE:4042398 kidney 5' read Protein similarity
  BG720505 cDNA clone IMAGE:4823817 testis, cell line 5' read Protein similarity
  BG828400 cDNA clone IMAGE:4904174 rhabdomyosarcoma 5' read Protein similarity
  BI253777 cDNA clone IMAGE:5115223 choriocarcinoma 5' read Protein similarity
  BI767464 cDNA clone IMAGE:5206663 pooled lung and spleen 5' read Protein similarity
  BI912026 cDNA clone IMAGE:5215341 leukocyte 5' read Protein similarity
  BI913193 cDNA clone IMAGE:5243117 brain 5' read Protein similarity
  BI914131 cDNA clone IMAGE:5246250 brain 5' read Protein similarity
  BE791618 cDNA clone IMAGE:3940307 small cell carcinoma 5' read Protein similarity
  BE889885 cDNA clone IMAGE:3913448 leiomyosarcoma 5' read Protein similarity
  AU133125 cDNA clone NT2RP4001343 5' read Protein similarity
  BI760436 cDNA clone IMAGE:5185548 pooled colon, kidney, stomach 5' read Protein similarity
  BG334374 cDNA clone IMAGE:4578576 melanotic melanoma 5' read
  BI833539 cDNA clone IMAGE:5227012 pooled pancreas and spleen 5' read Protein similarity
  AW239143 cDNA clone IMAGE:2577838 lung, cell line 5' read Protein similarity
  BF306389 cDNA clone IMAGE:4138817 rhabdomyosarcoma 5' read Protein similarity
  BI488632 cDNA clone IMAGE:5191935 brain 5' read Protein similarity
  AA075971 cDNA clone IMAGE:531456 5' read Protein similarity