Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.274170
Description:Opa-interacting protein 2
Best-Of-UniGene (BOU) SequenceAL050353
Genomic Coordiantes Displayed:Bases 2762135 to 2794862 of contig Hs13_10141_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.274170.jpeg
Best sense EST/protein match:BE379789 matched gb|AAC39558.1| (AF025438) Opa-interacting protein OIP2 [Homo sapiens] (E = e-109)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BG622466 cDNA clone IMAGE:4768722 placenta 5' read
  AL037717 cDNA clone DKFZp564A217 brain 3' read Protein similarityPolyadenylation signal
  AI963259 cDNA clone IMAGE:2508889 uterus 3' read 2.1 kb
  AI758998 cDNA clone IMAGE:2286928 uterus 3' read 3.6 kb
  R16194 cDNA clone IMAGE:52995 brain 3' read
  AI949541 cDNA clone IMAGE:2472060 stomach 3' read 1.9 kb
  AW249975 cDNA clone IMAGE:2821821 small cell carcinoma 3' read
  AI022083 cDNA clone IMAGE:1655041 pool 3' read 0.9 kb
  BG034315 cDNA clone IMAGE:4403879 mammary adenocarcinoma, cell line 5' read
  N22400 cDNA clone IMAGE:254458 ear 3' read 0.5 kb
  BE350931 cDNA clone IMAGE:3147362 2 pooled wilms' tumors, one primary and one metastatic to 3' read
  AI683470 cDNA clone IMAGE:2263266 uterus 3' read 2.4 kb
  W87682 cDNA clone IMAGE:417201 pool 3' read 0.8 kb
  AW150856 cDNA clone IMAGE:2630112 uterus 3' read
  Z40072 cDNA clone c1qh01 brain 3' read
  AW150498 cDNA clone IMAGE:2629296 uterus 3' read
  AW189100 cDNA clone IMAGE:2674920 uterus 3' read
  AI624085 cDNA clone IMAGE:2231175 uterus 3' read 3.3 kb
  F03294 cDNA clone c1sd10 brain 3' read
  AI799213 cDNA clone IMAGE:2261484 uterus 3' read 0.9 kbPolyadenylation signal
  AI368255 cDNA clone IMAGE:1991285 uterus 3' read 2.9 kbPolyadenylation signal
  BE049261 cDNA clone IMAGE:2836075 pancreas 3' read
  BG698682 cDNA clone IMAGE:4800280 skin 5' read
  Z44096 cDNA clone c1sd10 brain
  BF789864 cDNA clone IMAGE:4328160 muscle (skeletal) 5' read
  BI871380 cDNA clone IMAGE:5404515 adenocarcinoma, cell line 5' read
  AA343032 cDNA clone ATCC:144517 spleen 3' read
  AA305699 cDNA clone ATCC:129133 5' read Protein similarity

SENSE ESTs

  BG496153 cDNA clone IMAGE:4659621 mucoepidermoid carcinoma 5' read
  BG496297 cDNA clone IMAGE:4659688 mucoepidermoid carcinoma 5' read
  BG614353 cDNA clone IMAGE:4773590 embryonal carcinoma 5' read
  BG540700 cDNA clone IMAGE:4694898 lung 5' read Protein similarity
  BF248476 cDNA clone IMAGE:4046172 melanotic melanoma, high mdr 5' read
  BF214199 cDNA clone IMAGE:4079317 from acute myelogenous leukemia 5' read
  BG615237 cDNA clone IMAGE:4774889 embryonal carcinoma 5' read
  BF382648 cDNA clone IMAGE:4050996 primitive neuroectoderm 5' read
  BG569005 cDNA clone IMAGE:4722604 liver 5' read Protein similarity
  BG535730 cDNA clone IMAGE:4688532 lung 5' read Protein similarity
  BG611342 cDNA clone IMAGE:4738151 adenocarcinoma 5' read Protein similarity
  BF670204 cDNA clone IMAGE:4281373 primitive neuroectoderm 5' read
  BF218153 cDNA clone IMAGE:4104161 glioblastoma 5' read
  BG504459 cDNA clone IMAGE:4664887 embryonal carcinoma 5' read
  AV762968 cDNA clone MDSBHF09 bone marrow 5' read
  BF216688 cDNA clone IMAGE:4095503 glioblastoma 5' read
  BI917024 cDNA clone IMAGE:5245395 brain 5' read
  R17187 cDNA clone IMAGE:31926 brain 5' read 0.6 kbProtein similarity
  BE865991 cDNA clone IMAGE:3961109 carcinoma, cell line 5' read
  BG393475 cDNA clone IMAGE:4540786 embryonal carcinoma, cell line 5' read
  AV715050 cDNA clone DCBAID05 5' read Protein similarity
  BI771611 cDNA clone IMAGE:5208320 pooled lung and spleen 5' read
  N56244 cDNA clone J9729 heart 5' read Protein similarity
  BF173106 cDNA clone (no-name) blood
  BE379789 cDNA clone IMAGE:3511112 carcinoma, cell line 3' read Protein similarity
  R58666 cDNA clone G4584 heart 5' read
  BG697677 cDNA clone IMAGE:4803896 skin 5' read Protein similarity
  BG679830 cDNA clone IMAGE:4751215 squamous cell carcinoma 5' read Protein similarityPolyadenylation signal
  AA865602 cDNA clone IMAGE:1455870 kidney 3' read 0.8 kbProtein similarityPolyadenylation signal
  AW152251 cDNA clone IMAGE:2630027 uterus 3' read Protein similarityPolyadenylation signal
  AI753758 cDNA clone HBMSC_cr14g09 bone 3' read Protein similarityPolyadenylation signal
  AW151295 cDNA clone IMAGE:2630716 uterus 3' read
  AA680352 cDNA clone IMAGE:430477 pool 3' read Protein similarityPolyadenylation signal
  R41738 cDNA clone IMAGE:31926 brain 3' read 0.6 kbProtein similarityPolyadenylation signal
  AI539552 cDNA clone IMAGE:2189479 uterus 3' read Protein similarityPolyadenylation signal
  BE349061 cDNA clone IMAGE:3149998 malignant melanoma, metastatic to lymph node 3' read Protein similarityPolyadenylation signal
  AI678339 cDNA clone IMAGE:2257409 stomach 3' read 0.7 kbProtein similarityPolyadenylation signal
  T26930 cDNA clone CDDIR481 3' read Polyadenylation signal
  AA382667 cDNA clone ATCC:187000 testis 5' read
  AA382666 cDNA clone ATCC:187000 testis 3' read Polyadenylation signal