Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.296770
Description:KIAA1719 protein
Best-Of-UniGene (BOU) SequenceAB051506
Genomic Coordiantes Displayed:Bases 2934961 to 2986915 of contig Hs3_5925_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.296770.jpeg
Best sense EST/protein match:AB051506 matched dbj|BAB21810.1| (AB051506) KIAA1719 protein [Homo sapiens] (E = 0.0)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AI919555 cDNA clone IMAGE:2188604 stomach 3' read 3.1 kbPolyadenylation signal
  AI982622 cDNA clone IMAGE:2508101 uterus 3' read Polyadenylation signal
  AI983429 cDNA clone IMAGE:2510768 pancreas 3' read 0.7 kbPolyadenylation signal
  AW591874 cDNA clone IMAGE:2839015 uterus 3' read Polyadenylation signal
  AW517625 cDNA clone IMAGE:2791918 uterus 3' read Polyadenylation signal
  AI287513 cDNA clone IMAGE:1988459 uterus 3' read 1.0 kb
  AI289973 cDNA clone IMAGE:1988461 uterus 3' read 1.2 kbPolyadenylation signal
  AI520945 cDNA clone IMAGE:2183476 stomach 3' read 1.2 kbPolyadenylation signal
  AI886637 cDNA clone IMAGE:2440373 uterus 3' read 1.3 kbPolyadenylation signal
  AI538361 cDNA clone IMAGE:2204107 uterus 3' read 1.7 kbPolyadenylation signal
  AI564469 cDNA clone IMAGE:2212935 uterus 3' read Polyadenylation signal
  AW242210 cDNA clone IMAGE:2704842 pancreas 3' read
  AI932808 cDNA clone IMAGE:2457479 stomach 3' read 1.2 kbPolyadenylation signal
  BG170890 cDNA clone IMAGE:4426789 hypernephroma, cell line 5' read

SENSE ESTs

  BI759551 cDNA clone IMAGE:5187327 pooled colon, kidney, stomach 5' read Protein similarity
  R55592 cDNA clone IMAGE:40388 brain 5' read 1.9 kb
  R61039 cDNA clone IMAGE:42299 brain 5' read 2.0 kb
  T79979 cDNA clone IMAGE:24510 brain 5' read 2.1 kb
  R55354 cDNA clone IMAGE:40388 brain 3' read 1.9 kbPolyadenylation signal
  R60920 cDNA clone IMAGE:42299 brain 3' read 2.0 kbPolyadenylation signal