Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.300842
Description:KIAA1608 protein
Best-Of-UniGene (BOU) SequenceAB046828
Genomic Coordiantes Displayed:Bases 1702224 to 2498584 of contig Hs9_8689_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.300842.jpeg
Best sense EST/protein match:AB046828 matched dbj|BAB13434.1| (AB046828) KIAA1608 protein [Homo sapiens] (E = 0.0)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AI738848 cDNA clone IMAGE:2219764 ovary 3' read
  AI865442 cDNA clone IMAGE:2412173 lymph 3' read 0.8 kbPolyadenylation signal
  BF726291 cDNA clone by04e04 lens 3' read Polyadenylation signal
  AA586428 cDNA clone IMAGE:1104346 bone 3' read 0.4 kbPolyadenylation signal
  AA721043 cDNA clone IMAGE:1239248 bone 3' read 0.4 kbPolyadenylation signal
  BF341621 cDNA clone IMAGE:4152034 glioblastoma with egfr amplification 5' read
  AL048922 cDNA clone DKFZp434K1518 testis
  BE392023 cDNA clone IMAGE:3625401 endometrium, adenocarcinoma cell line 5' read
  BF344465 cDNA clone IMAGE:4150838 glioblastoma with egfr amplification 5' read
  BE393160 cDNA clone IMAGE:3627100 endometrium, adenocarcinoma cell line 5' read
  BF726292 cDNA clone by04e04 lens 5' read

SENSE ESTs

  BG283155 cDNA clone IMAGE:4518917 adenocarcinoma, cell line 5' read Protein similarity
  BE613942 cDNA clone IMAGE:3905823 leiomyosarcoma 5' read Protein similarity
  BI546376 cDNA clone IMAGE:5260192 hippocampus, cell line 5' read
  BI092952 cDNA clone IMAGE:4999484 placenta 5' read Protein similarity
  BG705190 cDNA clone IMAGE:4820404 hippocampus, cell line 5' read Protein similarity
  BG389427 cDNA clone IMAGE:4522468 embryonal carcinoma, cell line 5' read Protein similarity
  BI871410 cDNA clone IMAGE:5404619 adenocarcinoma, cell line 5' read Protein similarity
  BI762952 cDNA clone IMAGE:5188276 pooled colon, kidney, stomach 5' read Protein similarity
  BF981205 cDNA clone IMAGE:4400545 duodenal adenocarcinoma, cell line 5' read Protein similarity
  BE394596 cDNA clone IMAGE:3658972 endometrium, adenocarcinoma cell line 5' read Protein similarity
  BI334071 cDNA clone IMAGE:5139375 choriocarcinoma 5' read Protein similarity
  BI768439 cDNA clone IMAGE:5203800 pooled lung and spleen 5' read Protein similarity
  BG036131 cDNA clone IMAGE:4414143 adenocarcinoma, cell line 5' read
  BI861070 cDNA clone IMAGE:5406838 mammary adenocarcinoma, cell line 5' read Protein similarity
  BE614185 cDNA clone IMAGE:3905823 leiomyosarcoma 3' read
  AI500536 cDNA clone IMAGE:2177063 uterus 3' read 2.1 kbPolyadenylation signal
  BG106660 cDNA clone IMAGE:4385375 lymphoma, cell line 5' read
  AA360090 cDNA clone ATCC:164221 lung 5' read
  BG339687 cDNA clone IMAGE:4555263 leiomyosarcoma cell line 5' read Protein similarity
  BG290625 cDNA clone IMAGE:4517929 transitional cell papilloma, cell line 5' read
  BI913247 cDNA clone IMAGE:5243373 brain 5' read
  AL157682 cDNA clone DKFZp547P187 brain 5' read
  BG820381 cDNA clone IMAGE:4931311 anaplastic oligodendroglioma with 1p/19q loss 5' read
  BG485708 cDNA clone IMAGE:4644312 adenocarcinoma cell line 5' read
  BG823215 cDNA clone IMAGE:4866235 adenocarcinoma cell line 5' read
  D45297 cDNA clone (no-name) brain
  AW249128 cDNA clone IMAGE:2820991 small cell carcinoma 5' read
  BF128671 cDNA clone IMAGE:4053921 primary b-cells from tonsils (cell line) 5' read
  AV706833 cDNA clone ADBAXE11 adrenal gland 5' read
  BE546305 cDNA clone IMAGE:3457359 choriocarcinoma 5' read
  AV693736 cDNA clone GKCDHB08 hepatocellular carcinoma 5' read
  R51692 cDNA clone IMAGE:39134 brain 5' read 1.4 kb
  BG168162 cDNA clone IMAGE:4449637 hypernephroma, cell line 5' read
  BM055398 cDNA clone (no-name) islets of langerhans 5' read
  BG389104 cDNA clone IMAGE:4523044 embryonal carcinoma, cell line 5' read