Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.315463
Description:interleukin 24
Best-Of-UniGene (BOU) SequenceNM_006850
Genomic Coordiantes Displayed:Bases 1917552 to 1927378 of contig Hs1_4855_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.315463.jpeg
Best sense EST/protein match:NM_006850 matched ref|NP_006841.1| (NM_006850) suppression of tumorigenicity 16 (melanoma (E = e-109)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  AW242211 cDNA clone IMAGE:2704844 pancreas 3' read
  AI524407 cDNA clone IMAGE:2175201 lymph 3' read 0.3 kbPolyadenylation signal
  AW008256 cDNA clone IMAGE:2533169 stomach 3' read 1.0 kbPolyadenylation signal
  AI523387 cDNA clone IMAGE:2128132 aorta 3' read
  AI440057 cDNA clone IMAGE:2134983 lymph 3' read
  BE046111 cDNA clone IMAGE:2850776 lymph 3' read
  AA360238 cDNA clone ATCC:164346 lymph node 5' read
  AI880632 cDNA clone IMAGE:2354242 aorta 3' read


  AA370518 cDNA clone ATCC:175033 prostate 5' read Protein similarity
  BE788472 cDNA clone IMAGE:3878467 large cell carcinoma 5' read Protein similarity
  AA344685 cDNA clone ATCC:146229 gall bladder 5' read Protein similarity
  AI474086 cDNA clone IMAGE:2155661 colon 3' read 0.6 kbPolyadenylation signal
  BG939779 cDNA clone HBMSC_cr62a12 bone 3' read Polyadenylation signal