Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.339808
Description:hypothetical protein FLJ10120
Best-Of-UniGene (BOU) SequenceNM_018001
Genomic Coordiantes Displayed:Bases 33680 to 49220 of contig Hs17_26632_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.339808.jpeg
Best sense EST/protein match:AU118098 matched ref|NP_060471.1| (NM_018001) hypothetical protein FLJ10120 [Homo sapiens] (E = 1e-73)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AL121027 cDNA clone DKFZp762N233 melanoma (mewo cell line) 3' read Polyadenylation signal
  AW069695 cDNA clone HBMSC_cr51e12 bone 3' read
  BF688254 cDNA clone IMAGE:4299624 normal pigmented retinal epithelium 5' read
  BE019501 cDNA clone IMAGE:3010713 rhabdomyosarcoma 5' read
  BG422350 cDNA clone IMAGE:4585298 renal cell adenocarcinoma 5' read
  BE207352 cDNA clone IMAGE:2924129 renal cell adenocarcinoma 5' read Protein similarity
  BE275247 cDNA clone IMAGE:3346313 melanotic melanoma 5' read Protein similarity
  BE275822 cDNA clone IMAGE:3345917 melanotic melanoma 5' read Protein similarity
  BG287786 cDNA clone IMAGE:4513233 transitional cell papilloma, cell line 5' read
  BE799794 cDNA clone IMAGE:3946152 small cell carcinoma 5' read
  BG423489 cDNA clone IMAGE:4587898 renal cell adenocarcinoma 5' read
  BG823643 cDNA clone IMAGE:4868271 adenocarcinoma cell line 5' read
  BG475007 cDNA clone IMAGE:4620334 melanotic melanoma 5' read
  BE797466 cDNA clone IMAGE:3941876 small cell carcinoma 5' read
  BG168103 cDNA clone IMAGE:4449425 hypernephroma, cell line 5' read
  AA053543 cDNA clone IMAGE:510091 5' read 2.3 kbProtein similarity
  BE396292 cDNA clone IMAGE:3659096 endometrium, adenocarcinoma cell line 5' read Protein similarity
  BG826350 cDNA clone IMAGE:4902949 rhabdomyosarcoma 5' read
  BE379619 cDNA clone IMAGE:3510855 carcinoma, cell line 3' read Protein similarity
  BG741378 cDNA clone IMAGE:4777206 skin 5' read
  N84944 cDNA clone J1677 heart 5' read
  AA347391 cDNA clone ATCC:148642 heart 5' read
  BE380044 cDNA clone IMAGE:3510855 carcinoma, cell line 5' read
  AV692861 cDNA clone GKCBPD11 hepatocellular carcinoma 5' read
  AL603425 cDNA clone DKFZp686G177 human skeletal muscle 5' read
  BF105190 cDNA clone IMAGE:4042568 kidney 5' read
  BG471899 cDNA clone IMAGE:4635980 retinoblastoma 5' read
  BI856199 cDNA clone IMAGE:5391893 mammary adenocarcinoma, cell line 5' read
  BF338580 cDNA clone IMAGE:4182349 glioblastoma with egfr amplification 5' read
  BE409190 cDNA clone IMAGE:3630210 choriocarcinoma 5' read
  AA341366 cDNA clone ATCC:143021 kidney 5' read
  BG430801 cDNA clone IMAGE:4612457 kidney 5' read
  BG260104 cDNA clone IMAGE:4479742 transitional cell papilloma, cell line 5' read
  BI251908 cDNA clone IMAGE:5086782 hepatocellular carcinoma, cell line 5' read
  BI758675 cDNA clone IMAGE:5194433 brain 5' read
  H16917 cDNA clone IMAGE:50466 brain 5' read 1.3 kb
  AA317513 cDNA clone ATCC:117970 eye 5' read
  AA317660 cDNA clone ATCC:118118 eye 5' read
  BI768364 cDNA clone IMAGE:5203250 pooled lung and spleen 5' read
  AA361829 cDNA clone ATCC:166010 lymph 5' read
  BE779428 cDNA clone IMAGE:3867228 retinoblastoma 5' read
  AW023164 cDNA clone IMAGE:2486779 ear 5' read Polyadenylation signal
  AW023175 cDNA clone IMAGE:2486827 ear 5' read Polyadenylation signal
  AI270441 cDNA clone IMAGE:1979113 stomach 3' read 1.6 kb
  AA707129 cDNA clone IMAGE:452082 pool 3' read
  AL602041 cDNA clone DKFZp313N238 5' read
  AA593763 cDNA clone IMAGE:1073045 breast 3' read 0.3 kbPolyadenylation signal
  BF344847 cDNA clone IMAGE:4150017 glioblastoma with egfr amplification 5' read
  T56592 cDNA clone IMAGE:73134 spleen 3' read 0.8 kbPolyadenylation signal
  T57277 cDNA clone IMAGE:73134 spleen 5' read 0.8 kb
  BG724287 cDNA clone IMAGE:4829887 testis, cell line 5' read
  AV735241 cDNA clone cdAAJB04 pheochromocytoma 5' read
  AW276205 cDNA clone IMAGE:2759485 two pooled squamous cell carcinomas 3' read
  AW194369 cDNA clone IMAGE:2683640 uterus 3' read Polyadenylation signal
  Z39035 cDNA clone c0xf12 brain 3' read Polyadenylation signal
  AI963589 cDNA clone IMAGE:2492548 uterus 3' read 1.0 kbPolyadenylation signal
  AW276217 cDNA clone IMAGE:2759509 two pooled squamous cell carcinomas 3' read Polyadenylation signal
  AI459955 cDNA clone IMAGE:2151747 colon 3' read
  BG914356 cDNA clone IMAGE:4942977 anaplastic oligodendroglioma with 1p/19q loss 5' read
  AA092290 cDNA clone (no-name) heart 5' read
  AW771818 cDNA clone IMAGE:3006772 2 pooled wilms' tumors, one primary and one metastatic to 3' read
  BE208044 cDNA clone IMAGE:3010713 rhabdomyosarcoma 3' read
  AI632389 cDNA clone IMAGE:2181999 uterus 3' read
  AW517893 cDNA clone IMAGE:2806500 uterus 3' read
  AW079328 cDNA clone IMAGE:2580016 esophagus 3' read
  BG724210 cDNA clone IMAGE:4829705 testis, cell line 5' read
  AA298005 cDNA clone ATCC:193935 uterus 5' read
  BF447355 cDNA clone IMAGE:4091690 sympathetic trunk 3' read
  AW007655 cDNA clone IMAGE:2511579 pancreas 3' read
  AW263448 cDNA clone IMAGE:2757823 three pooled meningiomas 3' read
  T16770 cDNA clone NIB1824 brain 3' read
  AI634699 cDNA clone IMAGE:2288059 uterus 3' read 2.5 kb
  T32423 cDNA clone ATCC:102917 spleen 3' read
  BF689042 cDNA clone IMAGE:4299624 normal pigmented retinal epithelium 3' read
  AW022906 cDNA clone IMAGE:2486580 ear 5' read
  BI252549 cDNA clone IMAGE:5086782 hepatocellular carcinoma, cell line 3' read
  BG675310 cDNA clone IMAGE:4755219 skin 5' read
  AA369359 cDNA clone ATCC:174038 placenta 5' read
  AV715822 cDNA clone DCBBKD02 5' read
  AA310127 cDNA clone ATCC:156187 5' read
  BE253724 cDNA clone IMAGE:3353258 retinoblastoma 5' read
  BG392513 cDNA clone IMAGE:4539819 embryonal carcinoma, cell line 5' read
  BE379402 cDNA clone IMAGE:3609213 endometrium, adenocarcinoma cell line 5' read
  BE883406 cDNA clone IMAGE:3910647 leiomyosarcoma 5' read
  BE301121 cDNA clone IMAGE:2924129 renal cell adenocarcinoma 3' read
  AA358299 cDNA clone ATCC:162515 lung 5' read
  AA249616 cDNA clone (no-name) heart 5' read
  AA358019 cDNA clone ATCC:162325 lung 5' read
  AI673246 cDNA clone IMAGE:2264921 uterus 3' read 2.5 kbPolyadenylation signal
  AV729207 cDNA clone HTCAUC08 hypothalamus 5' read
  AA347043 cDNA clone ATCC:148399 heart 5' read

SENSE ESTs

  AU144749 cDNA clone HEMBA1002863 whole embryo, mainly head 3' read
  BG388088 cDNA clone IMAGE:4521778 embryonal carcinoma, cell line 5' read
  BG249885 cDNA clone IMAGE:4414397 hypernephroma, cell line 5' read
  AU118098 cDNA clone HEMBA1002863 whole embryo, mainly head 5' read
  N86274 cDNA clone J7481 heart 5' read Protein similarity
  BF345290 cDNA clone IMAGE:4153962 anaplastic oligodendroglioma with 1p/19q loss 5' read
  W85949 cDNA clone IMAGE:416053 pool 5' read 0.6 kb
  AW189256 cDNA clone IMAGE:2675157 uterus 3' read
  AI951999 cDNA clone IMAGE:2546142 four pooled pituitary adenomas 3' read Polyadenylation signal
  W85865 cDNA clone IMAGE:416053 pool 3' read 0.6 kb
  AI364580 cDNA clone IMAGE:1993316 uterus 3' read 2.3 kb
  AI963637 cDNA clone IMAGE:2492595 uterus 3' read 0.6 kbPolyadenylation signal
  AL046436 cDNA clone DKFZp434P127 testis 5' read Protein similarity
  BE547318 cDNA clone IMAGE:3460068 choriocarcinoma 5' read
  BG912503 cDNA clone IMAGE:4940588 anaplastic oligodendroglioma with 1p/19q loss 5' read
  BG537291 cDNA clone IMAGE:4689808 lung 5' read
  BF525420 cDNA clone IMAGE:4212553 glioblastoma with egfr amplification 5' read
  AL135072 cDNA clone DKFZp762A1612 melanoma (mewo cell line) 5' read