Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.347326
Description:intercellular adhesion molecule 2
Best-Of-UniGene (BOU) SequenceAK021786
Genomic Coordiantes Displayed:Bases 1132205 to 1163380 of contig Hs17_10855_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.347326.jpeg
Best sense EST/protein match:AU119233 matched ref|XP_044426.1| (XM_044426) hypothetical protein XP_044426 [Homo sapiens] (E = 4e-86)
Best antisense EST/protein match:BE260730 matched ref|XP_044428.1| (XM_044428) intercellular adhesion molecule 2 [Homo sapiens] (E = e-112)

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  AW166655 cDNA clone IMAGE:2633368 uterus 3' read Protein similarity
  BI837883 cDNA clone IMAGE:5222689 pooled pancreas and spleen 5' read Protein similarity
  AI289209 cDNA clone IMAGE:1899343 kidney 3' read 1.2 kbProtein similarity
  R42756 cDNA clone IMAGE:31273 brain 3' read 1.1 kb
  AA704988 cDNA clone IMAGE:462631 pool 3' read Protein similarity
  AA872937 cDNA clone IMAGE:1472607 kidney 3' read 0.7 kbProtein similarity
  AW316823 cDNA clone IMAGE:2836796 pancreas 3' read Protein similarity