Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.46829
Description:hypothetical protein FLJ21868
Best-Of-UniGene (BOU) SequenceNM_022769
Genomic Coordiantes Displayed:Bases 680000 to 820000 of contig Hs15_10522_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.46829.jpeg
Best sense EST/protein match:NM_022769 matched ref|NP_073606.1| (NM_022769) hypothetical protein FLJ21868 [Homo sapiens] (E = e-130)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BE901698 cDNA clone IMAGE:3960333 choriocarcinoma 5' read
  BE731997 cDNA clone IMAGE:3841639 choriocarcinoma 5' read
  BE902295 cDNA clone IMAGE:3959056 choriocarcinoma 5' read
  BE280546 cDNA clone IMAGE:3139378 choriocarcinoma 5' read
  BG479073 cDNA clone IMAGE:4649844 choriocarcinoma 5' read
  BG479751 cDNA clone IMAGE:4650612 choriocarcinoma 5' read
  BE901376 cDNA clone IMAGE:3957738 choriocarcinoma 5' read
  BE279148 cDNA clone IMAGE:3140159 choriocarcinoma 5' read
  BE281187 cDNA clone IMAGE:3140559 choriocarcinoma 5' read
  BE280233 cDNA clone IMAGE:3140597 choriocarcinoma 5' read


  BI194099 cDNA clone IMAGE:5089150 epithelioid carcinoma cell line 5' read Protein similarity