Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.58679
Description:solute carrier family 7, (cationic amino acid transporter, y+ system) member 10
Best-Of-UniGene (BOU) SequenceNM_019849
Genomic Coordiantes Displayed:Bases 920000 to 955000 of contig Hs19_11397_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.58679.jpeg
Best sense EST/protein match:BI754386 matched ref|NP_062823.1| (NM_019849) solute carrier family 7, member 10; asc-type amino acid (E = e-132)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BI753523 cDNA clone IMAGE:5197145 brain 5' read
  BI911593 cDNA clone IMAGE:5213155 leukocyte 5' read
  AW050439 cDNA clone IMAGE:2557787 uterus 3' read 0.7 kbPolyadenylation signal
  AW050434 cDNA clone IMAGE:2557786 uterus 3' read 0.7 kbPolyadenylation signal
  AI366865 cDNA clone IMAGE:1989206 uterus 3' read 0.3 kbPolyadenylation signal
  BE382484 cDNA clone IMAGE:3627592 neuroblastoma 5' read
  AA335242 cDNA clone ATCC:136922 testis 5' read
  BF980949 cDNA clone IMAGE:4401576 duodenal adenocarcinoma, cell line 5' read
  BF342997 cDNA clone IMAGE:4152768 glioblastoma with egfr amplification 5' read
  BE019311 cDNA clone IMAGE:3010509 rhabdomyosarcoma 5' read
  AA326386 cDNA clone ATCC:126916 brain 5' read


  BG709630 cDNA clone IMAGE:4796275 hypothalamus, cell line 5' read Protein similarity
  BI522792 cDNA clone IMAGE:5240227 brain 5' read Protein similarity
  BI756372 cDNA clone IMAGE:5200601 brain 5' read Protein similarity
  BI912797 cDNA clone IMAGE:5240697 brain 5' read Protein similarity
  BI754386 cDNA clone IMAGE:5197476 brain 5' read Protein similarity