Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.64639
Description:glioma pathogenesis-related protein
Best-Of-UniGene (BOU) SequenceNM_006851
Genomic Coordiantes Displayed:Bases 90500 to 94000 of contig Hs12_9613_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.64639.jpeg
Best sense EST/protein match:BF678939 matched ref|NP_006842.1| (NM_006851) glioma pathogenesis-related protein [Homo sapiens] (E = e-100)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AI755207 cDNA clone HBMSC_cr36h12 bone 3' read Protein similarity
  R20401 cDNA clone IMAGE:32775 brain 5' read 2.1 kb
  T16979 cDNA clone NIB20965R brain 5' read
  BG170166 cDNA clone IMAGE:4424900 hypernephroma, cell line 5' read
  AA364358 cDNA clone ATCC:169296 brain 5' read
  BG533289 cDNA clone IMAGE:4072022 liver 5' read Protein similarity
  BG500035 cDNA clone IMAGE:4668512 adenocarcinoma 5' read
  BF132241 cDNA clone IMAGE:4052067 hypernephroma 5' read
  BF030939 cDNA clone IMAGE:3828614 hypernephroma 5' read
  AI536909 cDNA clone IMAGE:2178987 uterus 3' read 1.0 kb
  BF031929 cDNA clone IMAGE:3829187 hypernephroma 5' read Protein similarity
  BG531104 cDNA clone IMAGE:4699274 embryonal carcinoma 5' read
  BF207974 cDNA clone IMAGE:4082039 carcinoma, cell line 5' read Protein similarity
  BI259714 cDNA clone IMAGE:5110809 choriocarcinoma 5' read Protein similarity
  BF570681 cDNA clone IMAGE:4242975 melanotic melanoma, high mdr 5' read
  BG340143 cDNA clone IMAGE:4555398 leiomyosarcoma cell line 5' read

SENSE ESTs

  AV762281 cDNA clone MDSCHC10 bone marrow 5' read Protein similarity
  AV733642 cDNA clone cdABAF02 pheochromocytoma 5' read Protein similarity
  AA090829 cDNA clone (no-name) heart 5' read
  BE866363 cDNA clone IMAGE:3961868 carcinoma, cell line 5' read Protein similarity
  AL118849 cDNA clone DKFZp761J2111 amygdala 5' read Protein similarity
  N56188 cDNA clone J8419 heart 5' read Protein similarity
  AA375170 cDNA clone ATCC:179585 5' read
  W30991 cDNA clone IMAGE:310347 5' read 1.7 kbProtein similarity
  AV762100 cDNA clone MDSEOA02 bone marrow 5' read Protein similarity
  BI603126 cDNA clone IMAGE:5303847 hypothalamus, cell line 5' read Protein similarity
  BF216888 cDNA clone IMAGE:4095753 glioblastoma 5' read Protein similarity
  BF244194 cDNA clone IMAGE:4080705 glioblastoma 5' read Protein similarity
  BF340681 cDNA clone IMAGE:4183401 glioblastoma with egfr amplification 5' read Protein similarity
  BG165547 cDNA clone IMAGE:4453841 hypernephroma, cell line 5' read Protein similarity
  BF669517 cDNA clone IMAGE:4277407 primitive neuroectoderm 5' read Protein similarity
  BF678939 cDNA clone IMAGE:4294648 prostate 5' read Protein similarity
  W52836 cDNA clone IMAGE:326246 5' read 1.0 kbProtein similarity
  W48797 cDNA clone IMAGE:325190 5' read Protein similarity
  BG720406 cDNA clone IMAGE:4823904 testis, cell line 5' read Protein similarity
  AW103489 cDNA clone IMAGE:2595924 ovary 3' read Protein similarity
  AI248174 cDNA clone IMAGE:1849468 pool 3' read 0.8 kbProtein similarity
  AA777238 cDNA clone IMAGE:448219 pool 3' read Protein similarity
  BG573121 cDNA clone IMAGE:4721476 placenta 5' read Protein similarity
  AA862147 cDNA clone IMAGE:1485914 head and neck 3' read 1.0 kbProtein similarityPolyadenylation signal
  AA700371 cDNA clone IMAGE:460495 pool 3' read Protein similarity
  W49623 cDNA clone IMAGE:325190 3' read Protein similarity
  AA975359 cDNA clone IMAGE:1588689 kidney 3' read 1.2 kbProtein similarity
  D79966 cDNA clone GEN365E04 aorta 5' read Protein similarity
  BF030253 cDNA clone IMAGE:3828278 hypernephroma 5' read Protein similarity
  AA312938 cDNA clone ATCC:167791 bone 5' read
  AU142014 cDNA clone THYRO1001615 thyroid gland 5' read