Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.75709
Description:mannose-6-phosphate receptor (cation dependent)
Best-Of-UniGene (BOU) SequenceNM_002355
Genomic Coordiantes Displayed:Bases 426000 to 454000 of contig Hs12_9859_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.75709.jpeg
Best sense EST/protein match:AU130322 matched ref|NP_002346.1| (NM_002355) cation-dependent mannose-6-phosphate receptor (E = e-99)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  AW130547 cDNA clone IMAGE:2621715 stomach 3' read Polyadenylation signal
  AW192536 cDNA clone IMAGE:2677732 pancreas 3' read Polyadenylation signal
  R45234 cDNA clone IMAGE:35189 brain 3' read 1.9 kbPolyadenylation signal
  AW078486 cDNA clone IMAGE:2576677 2 pooled wilms' tumors, one primary and one metastatic to 3' read Polyadenylation signal
  N94324 cDNA clone IMAGE:309422 3' read Polyadenylation signal
  AI273890 cDNA clone IMAGE:1964290 ovary 3' read 2.5 kbPolyadenylation signal
  AI749574 cDNA clone IMAGE:2373547 colon 3' read Polyadenylation signal
  AW051209 cDNA clone IMAGE:2557572 uterus 3' read Polyadenylation signal
  AW169295 cDNA clone IMAGE:2657912 uterus 3' read Polyadenylation signal
  AI956148 cDNA clone IMAGE:2509480 pancreas 3' read Polyadenylation signal
  AI963013 cDNA clone IMAGE:2508559 uterus 3' read 0.5 kbPolyadenylation signal
  AW439285 cDNA clone IMAGE:2778824 uterus 3' read Polyadenylation signal
  AW090406 cDNA clone IMAGE:2590729 brain 3' read Polyadenylation signal
  F03237 cDNA clone c1qf04 brain 3' read Polyadenylation signal
  AI888684 cDNA clone IMAGE:2447347 stomach 3' read 3.2 kbPolyadenylation signal
  AU152962 cDNA clone NT2RP3002094 3' read Polyadenylation signal
  AU144205 cDNA clone HEMBA1001214 whole embryo, mainly head 3' read Polyadenylation signal
  AU149418 cDNA clone NT2RM4002274 3' read Polyadenylation signal
  AI571509 cDNA clone IMAGE:2225080 pancreas 3' read Polyadenylation signal
  AU151693 cDNA clone NT2RP2005866 3' read Polyadenylation signal
  H69929 cDNA clone IMAGE:239205 nose 3' read
  AA179832 cDNA clone IMAGE:613186 3' read
  AA700293 cDNA clone IMAGE:460745 pool 3' read
  AV708082 cDNA clone ADCAPD02 adrenal gland 5' read
  BE909007 cDNA clone IMAGE:3899824 epithelioid carcinoma 5' read
  AA285307 cDNA clone (no-name) 5' read