Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.80618
Description:hypothetical protein
Best-Of-UniGene (BOU) SequenceAK056421
Genomic Coordiantes Displayed:Bases 226670 to 260741 of contig Hs17_25030_24
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingHs.80618.jpeg
Best sense EST/protein match:AK056421 matched dbj|BAB71179.1| (AK056421) unnamed protein product [Homo sapiens] (E = 0.0)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  Z42298 cDNA clone c0eg06 brain Protein similarity
  T17032 cDNA clone NIB21905R brain 5' read
  T23835 cDNA clone b4HB3MACot8-HAP-Ft-226 brain 5' read
  R67162 cDNA clone IMAGE:42589 brain 5' read 1.0 kb
  R61085 cDNA clone IMAGE:42533 brain 5' read 1.2 kbProtein similarity
  R59981 cDNA clone IMAGE:42589 brain 3' read 1.0 kb
  R61808 cDNA clone IMAGE:42533 brain 3' read 1.2 kb
  AI347290 cDNA clone IMAGE:1916446 kidney 3' read 1.2 kb


  AA303374 cDNA clone ATCC:114956 aorta 5' read
  N86020 cDNA clone J6076 heart 5' read
  AW474094 cDNA clone IMAGE:2852712 lymph 3' read Polyadenylation signal
  AW090104 cDNA clone IMAGE:2591607 brain 3' read Polyadenylation signal
  AA701863 cDNA clone IMAGE:434776 pool 3' read Polyadenylation signal
  BE567461 cDNA clone IMAGE:3682942 carcinoma, cell line 5' read
  AI720247 cDNA clone IMAGE:2335415 colon 3' read
  AI720136 cDNA clone IMAGE:2334797 colon 3' read
  AA156335 cDNA clone IMAGE:590732 3' read
  AW148943 cDNA clone IMAGE:2617340 kidney 3' read
  BI497060 cDNA clone IMAGE:2537536 ear 5' read
  AI056208 cDNA clone IMAGE:1673538 pool 3' read 1.6 kb
  AA156370 cDNA clone IMAGE:590732 5' read