Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.82547
Description:retinoic acid receptor responder (tazarotene induced) 1
Best-Of-UniGene (BOU) SequenceNM_002888
Genomic Coordiantes Displayed:Bases 354000 to 396000 of contig Hs3_5958_24
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingHs.82547.jpeg
Best sense EST/protein match:NM_002888 matched ref|NP_002879.1| (NM_002888) retinoic acid receptor responder (tazarotene induced) 1 (E = e-101)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BE010425 cDNA clone (no-name) breast_normal
  BI561634 cDNA clone IMAGE:5298324 testis, cell line 5' read
  AV708656 cDNA clone ADCADA01 adrenal gland 5' read Protein similarity
  BI562071 cDNA clone IMAGE:5299017 testis, cell line 5' read Protein similarity
  AA383621 cDNA clone ATCC:187793 testis 5' read


  AI784017 cDNA clone IMAGE:2180444 uterus 3' read 0.6 kbPolyadenylation signal
  AI370216 cDNA clone IMAGE:1967651 lymph 3' read 1.3 kb
  AW084931 cDNA clone IMAGE:2589172 esophagus 3' read Polyadenylation signal
  BE049611 cDNA clone IMAGE:2835366 pancreas 3' read Polyadenylation signal
  AI301711 cDNA clone IMAGE:1900385 kidney 3' read 1.9 kb
  AA693445 cDNA clone IMAGE:1157177 kidney 3' read Polyadenylation signal
  AW513526 cDNA clone IMAGE:2707063 uterus 3' read Polyadenylation signal
  AA969462 cDNA clone IMAGE:1572590 kidney 3' read 1.8 kbPolyadenylation signal
  N94424 cDNA clone IMAGE:309583 3' read 1.2 kb
  AI691044 cDNA clone IMAGE:2208729 uterus 3' read 1.6 kbPolyadenylation signal
  AW078671 cDNA clone IMAGE:2575155 2 pooled high-grade transitional cell tumors 3' read Polyadenylation signal
  AW474961 cDNA clone IMAGE:2881960 stomach 3' read Polyadenylation signal
  AI335169 cDNA clone IMAGE:1915332 kidney 3' read 3.1 kb
  AW664482 cDNA clone IMAGE:2972128 2 pooled high-grade transitional cell tumors 3' read Polyadenylation signal
  AA366172 cDNA clone ATCC:170980 pancreas 5' read Protein similarity
  AI887421 cDNA clone IMAGE:2435040 uterus 3' read 0.9 kbProtein similarity
  W30772 cDNA clone IMAGE:309583 5' read 1.2 kbProtein similarity
  AW514087 cDNA clone IMAGE:2792817 uterus 3' read Protein similarityPolyadenylation signal
  BG742210 cDNA clone IMAGE:4776506 skin 5' read Protein similarity
  BG484662 cDNA clone IMAGE:4619385 lung 5' read Protein similarity