Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.196572
Description:coactivator-associated arginine methyltransferase 1
Best-Of-UniGene (BOU) SequenceNM_021531
Genomic Coordiantes Displayed:Bases 11338851 to 11371228 of contig GA_x5J8B7W6RL5
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingMm.196572.jpeg
Best sense EST/protein match:BI149777 matched gb|AAH03964.1|AAH03964 (BC003964) Unknown (protein for IMAGE:3488182) [Mus musculus] (E = e-105)
Best antisense EST/protein match:BI657028 matched gb|AAH02282.1|AAH02282 (BC002282) Similar to hypothetical protein [Mus musculus] (E = e-102)

This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

  BF165765 cDNA clone IMAGE:4018820 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read
  BG962170 cDNA clone IMAGE:4981737 colon 5' read Protein similarity
  BE284956 cDNA clone IMAGE:3497525 tumor, gross tissue 5' read
  BI657028 cDNA clone IMAGE:5326527 tumor, gross tissue 5' read Protein similarity
  BF302252 cDNA clone IMAGE:4166284 salivary gland 5' read
  BF303171 cDNA clone IMAGE:4166270 salivary gland 5' read
  AA103461 cDNA clone IMAGE:554594 embryo 5' read
  BI452579 cDNA clone IMAGE:5249321 tumor, gross tissue 5' read Protein similarity
  BG293304 cDNA clone IMAGE:4502924 retina 5' read