Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.46412
Description:RIKEN cDNA 1110003P15 gene
Best-Of-UniGene (BOU) SequenceNM_023628
Genomic Coordiantes Displayed:Bases 993052 to 1019659 of contig GA_x5J8B7W4YB8
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingMm.46412.jpeg
Best sense EST/protein match:NM_023628 matched ref|NP_076117.1| (NM_023628) annexin A9 [Mus musculus] (E = 0.0)
Best antisense EST/protein match:BF136784 matched dbj|BAA92628.1| (AB037811) KIAA1390 protein [Homo sapiens] (E = e-122)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BI653644 cDNA clone IMAGE:5340695 tumor, gross tissue 5' read Polyadenylation signal
  AI647654 cDNA clone IMAGE:1971085 kidney 3' read Protein similarityPolyadenylation signal
  AI267096 cDNA clone IMAGE:1907672 kidney 3' read Polyadenylation signal
  BI794636 cDNA clone (no-name) 5' read Polyadenylation signal
  BG085166 cDNA clone H3109D02 5' read Polyadenylation signal
  AI313914 cDNA clone IMAGE:1922262 kidney 3' read Polyadenylation signal
  AU042288 cDNA clone J1016G07 3' read Polyadenylation signal
  BE634983 cDNA clone IMAGE:3413279 spleen 3' read Polyadenylation signal
  BG072333 cDNA clone H3109D02 3' read Polyadenylation signal
  BB510223 cDNA clone D730028F23 mammary gland
  AV286227 cDNA clone 5031420G17 ovary and uterus
  AV286743 cDNA clone 5031427A06 ovary and uterus
  BB511261 cDNA clone D730033B14 mammary gland
  AV286839 cDNA clone 5031428A15 ovary and uterus
  BB506491 cDNA clone D730008G19 mammary gland
  BB510786 cDNA clone D730031B16 mammary gland
  BB509779 cDNA clone D730026D14 mammary gland
  AA673392 cDNA clone IMAGE:1024772 muscle 5' read
  BF160215 cDNA clone IMAGE:3990342 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read
  BE287170 cDNA clone IMAGE:3488168 tumor, gross tissue 5' read
  BE307001 cDNA clone IMAGE:3482450 tumor, gross tissue 5' read
  BI143818 cDNA clone IMAGE:5064191 kidney 5' read Protein similarity
  BI110506 cDNA clone IMAGE:5026150 tumor, gross tissue 5' read Protein similarity
  BE633489 cDNA clone IMAGE:3413279 spleen 5' read Protein similarity
  AA036612 cDNA clone IMAGE:467307 embryo 5' read Protein similarity
  AA561103 cDNA clone IMAGE:977523 embryo 5' read Protein similarity
  BI153413 cDNA clone IMAGE:5065694 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  AA793360 cDNA clone IMAGE:989827 embryo 5' read Protein similarity
  BF180293 cDNA clone IMAGE:4037609 tumor, gross tissue 5' read Protein similarity
  BF134149 cDNA clone IMAGE:4007022 tumor, metastatic to mammary 5' read Protein similarity
  BI112955 cDNA clone IMAGE:5028141 tumor, gross tissue 5' read Protein similarity
  BF144336 cDNA clone IMAGE:4014924 tumor, metastatic to mammary 5' read Protein similarity
  BF140614 cDNA clone IMAGE:4014973 tumor, metastatic to mammary 5' read Protein similarity
  BI107245 cDNA clone IMAGE:5039263 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read
  BF136784 cDNA clone IMAGE:4010223 tumor, metastatic to mammary 5' read Protein similarity
  BF789383 cDNA clone IMAGE:4221726 kidney 5' read Protein similarity
  BG171971 cDNA clone IMAGE:4456314 tumor, biopsy sample 5' read Protein similarity
  BE374856 cDNA clone IMAGE:3585066 tumor, biopsy sample 5' read Protein similarity
  BG919528 cDNA clone IMAGE:4946989 infiltrating ductal carcinoma 5' read

SENSE ESTs

  AA896767 cDNA clone IMAGE:1295038 macrophage 5' read Protein similarity
  AA107731 cDNA clone IMAGE:556804 embryo 5' read Protein similarity
  BE569288 cDNA clone IMAGE:3708846 infiltrating ductal carcinoma 5' read
  BE571996 cDNA clone IMAGE:3711362 infiltrating ductal carcinoma 5' read