Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.944
Description:integral membrane glycoprotein
Best-Of-UniGene (BOU) SequenceNM_008377
Genomic Coordiantes Displayed:Bases 2783800 to 3072200 of contig GA_x5J8B7W46BC
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingMm.944.jpeg
Best sense EST/protein match:AA637949 matched ref|NP_032403.1| (NM_008377) integral membrane glycoprotein [Mus musculus] (E = e-101)
Best antisense EST/protein match:BI454859 matched dbj|BAB30050.1| (AK015954) Mitochondrial carrier proteins containing protein~data (E = 2e-52)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BE914686 cDNA clone IMAGE:3967488 tumor, biopsy sample 5' read Protein similarity
  BI153612 cDNA clone IMAGE:5003084 tumor, biopsy sample 5' read
  BI454859 cDNA clone IMAGE:5251510 tumor, gross tissue 5' read Protein similarity
  AI195032 cDNA clone IMAGE:1886738 liver 3' read Polyadenylation signal
  BG092556 cDNA clone IMAGE:3999720 spleen 3' read Polyadenylation signal
  BG092668 cDNA clone IMAGE:3999744 spleen 3' read Polyadenylation signal
  AI891477 cDNA clone IMAGE:2123318 kidney 3' read Polyadenylation signal
  AI891485 cDNA clone IMAGE:2123317 kidney 3' read Polyadenylation signal
  BI737293 cDNA clone IMAGE:5365186 retina 5' read Polyadenylation signal
  BG075791 cDNA clone H3151G10 3' read Polyadenylation signal
  BG090568 cDNA clone IMAGE:3999720 spleen 5' read
  BG091359 cDNA clone IMAGE:3999744 spleen 5' read
  BI686468 cDNA clone IMAGE:5353042 infiltrating ductal carcinoma 5' read
  AA237671 cDNA clone IMAGE:679883 liver 5' read Protein similarity

SENSE ESTs

  BF146752 cDNA clone IMAGE:3660514 tumor, metastatic to mammary 3' read Polyadenylation signal
  AA002558 cDNA clone IMAGE:427620 embryo 5' read
  AA008358 cDNA clone IMAGE:438805 embryo 5' read
  W78554 cDNA clone IMAGE:401818 embryo 5' read
  AW208752 cDNA clone IMAGE:2647236 tumor, biopsy sample 3' read Polyadenylation signal
  BF141639 cDNA clone IMAGE:4016777 tumor, metastatic to mammary 5' read
  W34860 cDNA clone IMAGE:353095 embryo 5' read
  W34700 cDNA clone IMAGE:352863 embryo 5' read
  AA881125 cDNA clone IMAGE:1314959 mammary gland 5' read
  AA261247 cDNA clone IMAGE:747849 liver 5' read
  AA472700 cDNA clone IMAGE:875209 mammary gland 5' read
  W57155 cDNA clone IMAGE:372522 embryo 5' read
  W61717 cDNA clone IMAGE:372529 embryo 5' read
  BF142668 cDNA clone IMAGE:4020482 tumor, metastatic to mammary 5' read
  W83922 cDNA clone IMAGE:406913 embryo 5' read
  BF015919 cDNA clone IMAGE:3660514 tumor, metastatic to mammary 5' read
  BF537997 cDNA clone IMAGE:4188731 salivary gland 5' read
  BE533096 cDNA clone IMAGE:3596055 infiltrating ductal carcinoma 5' read Protein similarity
  AL361483 cDNA clone M9128A32 embryo 5' read Protein similarity
  BF607511 cDNA clone ICRFp522H0254 whole embryo 5' read Protein similarity
  AW230432 cDNA clone IMAGE:2647236 tumor, biopsy sample 5' read Protein similarity
  BF101367 cDNA clone IMAGE:3980536 tumor, biopsy sample 5' read Protein similarity
  AI153858 cDNA clone IMAGE:1449245 mammary gland 5' read Protein similarity
  AA103605 cDNA clone IMAGE:555998 embryo 5' read Protein similarity
  D77032 cDNA clone 94A08 embryonal carcinoma Protein similarity
  AA637949 cDNA clone IMAGE:1121390 muscle 5' read Protein similarity
  BG920848 cDNA clone IMAGE:4953488 infiltrating ductal carcinoma 5' read Protein similarity
  BE368251 cDNA clone IMAGE:3590708 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  BG964043 cDNA clone IMAGE:4983788 colon 5' read Protein similarity
  AW320514 cDNA clone IMAGE:2609635 infiltrating ductal carcinoma 5' read Protein similarity
  BF022068 cDNA clone IMAGE:3662607 tumor, metastatic to mammary 5' read Protein similarity
  BF540423 cDNA clone IMAGE:4189677 salivary gland 5' read Protein similarity
  BI651587 cDNA clone IMAGE:5338934 tumor, gross tissue 5' read Protein similarity
  BF160799 cDNA clone IMAGE:3990312 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  BF538423 cDNA clone IMAGE:4192996 salivary gland 5' read Protein similarity
  BE370488 cDNA clone IMAGE:3587222 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  AA048374 cDNA clone IMAGE:477450 embryo 5' read
  BG961952 cDNA clone IMAGE:4981214 colon 5' read