Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.9821
Description:SA rat hypertension-associated homolog
Best-Of-UniGene (BOU) SequenceNM_016870
Genomic Coordiantes Displayed:Bases 3064000 to 3106000 of contig GA_x5J8B7W4RT3
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingMm.9821.jpeg
Best sense EST/protein match:AA237778 matched gb|AAH15248.1|AAH15248 (BC015248) SA rat hypertension-associated homolog [Mus musculus] (E = e-109)
Best antisense EST/protein match:AI157014 matched ref|XP_031461.1| (XM_031461) KIAA1504 protein [Homo sapiens] (E = 6e-47)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AA839667 cDNA clone IMAGE:1433794 uterus 5' read Protein similarity
  AI606618 cDNA clone IMAGE:1433794 uterus 5' read Protein similarity
  AI157014 cDNA clone IMAGE:1434773 uterus 5' read Protein similarity
  AA118077 cDNA clone IMAGE:537380 embryo 5' read
  AW229239 cDNA clone IMAGE:2598912 infiltrating ductal carcinoma 5' read
  BG081048 cDNA clone H3060E07 5' read
  C88237 cDNA clone J0258H11 embryo 3' read Protein similarity
  BG067990 cDNA clone H3060E07 3' read Protein similarity
  BI655049 cDNA clone IMAGE:5326758 tumor, gross tissue 5' read Protein similarityPolyadenylation signal
  AI666758 cDNA clone IMAGE:1433794 uterus 3' read Protein similarityPolyadenylation signal
  AI426961 cDNA clone IMAGE:537380 embryo 3' read Protein similarityPolyadenylation signal
  BG975718 cDNA clone IMAGE:4980778 tumor, gross tissue 5' read Protein similarityPolyadenylation signal
  BI657412 cDNA clone IMAGE:5326831 tumor, gross tissue 5' read Protein similarityPolyadenylation signal

SENSE ESTs

  BG972014 cDNA clone IMAGE:4975780 kidney 5' read
  BF783604 cDNA clone IMAGE:4237827 kidney 5' read Protein similarity
  BF786970 cDNA clone IMAGE:4240048 kidney 5' read
  BI439998 cDNA clone (no-name) 3' read Polyadenylation signal
  AA237778 cDNA clone IMAGE:692409 liver 5' read Protein similarity
  AV285827 cDNA clone 5031414G21 ovary and uterus
  BI100656 cDNA clone IMAGE:5041249 kidney 5' read Protein similarity
  BI100333 cDNA clone IMAGE:5041225 kidney 5' read Protein similarity
  AA879670 cDNA clone IMAGE:1230324 mammary gland 5' read Protein similarity
  BF784906 cDNA clone IMAGE:4239542 kidney 5' read Protein similarity
  BI440405 cDNA clone (no-name) 5' read Protein similarity
  BG971652 cDNA clone IMAGE:4975090 kidney 5' read Protein similarity
  BF780185 cDNA clone IMAGE:4222264 kidney 5' read Protein similarity
  BG971236 cDNA clone IMAGE:4974181 kidney 5' read Protein similarity
  BI102427 cDNA clone IMAGE:5044706 kidney 5' read Protein similarity
  BI101304 cDNA clone IMAGE:5042529 kidney 5' read Protein similarity
  BG969522 cDNA clone IMAGE:4971236 kidney 5' read Protein similarity
  BG973001 cDNA clone IMAGE:4975289 kidney 5' read Protein similarity
  BI099997 cDNA clone IMAGE:5040105 kidney 5' read Protein similarity
  BI100412 cDNA clone IMAGE:5041199 kidney 5' read Protein similarity
  BI101540 cDNA clone IMAGE:5042864 kidney 5' read Protein similarity
  AW761801 cDNA clone IMAGE:2803492 thymus 5' read Protein similarity
  BI103751 cDNA clone IMAGE:5040701 kidney 5' read Protein similarity
  BF787959 cDNA clone IMAGE:4241317 kidney 5' read Protein similarity
  BB617401 cDNA clone 5031414G21 ovary and uterus Protein similarity
  BF785986 cDNA clone IMAGE:4239801 kidney 5' read Protein similarity
  BF383663 cDNA clone IMAGE:4194037 liver 5' read Protein similarity
  BF780869 cDNA clone IMAGE:4223726 kidney 5' read Protein similarity
  BF781996 cDNA clone IMAGE:4234980 kidney 5' read Protein similarity
  BF782283 cDNA clone IMAGE:4234433 kidney 5' read Protein similarity
  BF784432 cDNA clone IMAGE:4238933 kidney 5' read Protein similarity
  BF784748 cDNA clone IMAGE:4239286 kidney 5' read Protein similarity
  BF784848 cDNA clone IMAGE:4239288 kidney 5' read Protein similarity
  AW227404 cDNA clone IMAGE:2286593 kidney 5' read Protein similarity