Dr. Sukhdeep (Bobby) Singh Dhadwar, PhD.

Email: sdhadwar@genetic.med.harard.eu

Primary Research Project: Age-reversal, anti-ageing & longevity

The Aging Process

Ageing affects our ability to function and respond to stress while increasing risk of disease and mortality. Families of long-lived individuals, specifically supercentenarians, suggests the presence of rare protective alleles that preserve health, cognitive functions and other biological functions at advanced ages. There have been a number of biomarkers identified to track the ageing process and provide an ageing rate or biological age that may diverge from chronological age.

Age reversal project

The primary project is to examine ways of reversing the ageing phenotype in a system that is translatable to humans. Genetic and epigenetic modifiers are being explored to alter the ageing process in a human system without altering the identity of the cell or tissue. The rejuvenation of aged cells to a more youthful state is verified using multiple ageing biomarkers. This project has the potential to have a profound impact on the lives of the ageing population and address age-related disorders.

About me:

I am a postdoctoral Fellow in the George Church lab. I have a background in Environmental, Chemical and Biomedical Engineering. My previous research includes designing treatment/imaging strategies for breast cancer and developing a gene therapy products for hemophilia. I am now interested in correcting age-associated diseases by delaying or preventing the progression of the aging phenotype.