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ACUUAU M1,6= S = fAU log2[fAU/(fA*fU)]...

CCUUAG x1x6

GCUUGC =4*.25log2[.25/(.25*.25)]=2

UCUUGA

i=1 j=6 M1,2= 4*.25log2[.25/(.25*1)]=0

Mij= Sfxixjlog2[fxixj/(fxifxj)] M=0 to 2 bits; x=base type

xixj see Durbin et al p. 266-8.

See Shannon entropy, multinomial Grendar

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