Transmembrane prediction
J Mol Biol 2001 Oct 5;312(5):927-34 Energetics, stability, and prediction of transmembrane helices. Jayasinghe et al.
Backbone constraint, identifies TM helices of membrane proteins with an accuracy greater than 99 %. (& energetics of salt-bridge formation. Falsely predicts 17 to 43 % of a set of soluble proteins to be MPs, depending upon the hydropathy scale used