Dynamic Mass Balance: ColE1 RNAI[concentration in moles/liter]

Rate of change

of [RNA I]

Synthesis of

RNA I

Degradation

of RNA I

Dilution due

to cell growth

=

-

-

R = [RNA I]

k1 = rate of RNA I initiation

N = [plasmid]

kd = rate of degradation

m = growth rate

Keasling,& Palsson (1989) J theor Biol 136, 487-492; 141, 447-61.

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