3D-structure to function to morphology to function

www.wadsworth.org/chemheme/heme/cytocritique

Echinocytes (crenated);

hyperosmotic medium

Dacrocytes;

pernicious anemia

Acanthocytes;

abetalipoproteinemia

Macrocytes 9-12µm;

megaloblastic anemia

Spherocytes;

enzyme deficiencies

Sickle cell;

HbS

Normal RBC 6-8 µm;

4e12 per L

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