Ratio of strains
times, te , selection coefficients, se,
80% of 34 random yeast insertions have s<-0.3% or sɬ.3%
t=160 generations, e=1 (rich media); ~50% for t=15, e=7.
Should allow comparisons with population allele models.
Multiplex competitive growth experiments:
Thatcher, et al. (1998) PNAS 95:253.
Link AJ (1994) thesis; (1997) J Bacteriol 179:6228.
Smith V, et al. (1995) PNAS 92:6479.
Shoemaker D, et al. (1996) Nat Genet 14:450.