Cluster 1

 

let-7f (M.m.; 4)           TGAGGTAGTAGATTGTATAGTT--

let-7f (H.s.; 3)           TGAGGTAGTAGATTGTATAGTT--

let-7g (M.m.; 4)           TGAGGTAGTAGTTTGTACAGTA--

let-7i (M.m.; 4)           TGAGGTAGTAGTTTGTGCT-----

let-7h (M.m.; 4)           TGAGGTAGTAGTGTGTACAGTT--

let-7e (M.m.; 4)           TGAGGTAGGAGGTTGTATAGT---

let-7e (H.s.; 3)           TGAGGTAGGAGGTTGTATAGT---

let-7d (M.m.; 4)           AGAGGTAGTAGGTTGCATAGT---

let-7d (H.s.; 3)           AGAGGTAGTAGGTTGCATAGT---

let-7a (H.s.; 3)           TGAGGTAGTAGGTTGTATAGTT--

let-7a (M.m.; 4)           TGAGGTAGTAGGTTGTATAGTT--

let-7 (C.e.; 2)            TGAGGTAGTAGGTTGTATAGTT--

let-7b (M.m.; 4)           TGAGGTAGTAGGTTGTGTGGTT--

let-7b (H.s.; 3)           TGAGGTAGTAGGTTGTGTGGTT--

let-7c (M.m.; 4)           TGAGGTAGTAGGTTGTATGGTT--

let-7c (H.s.; 3)           TGAGGTAGTAGGTTGTATGGTT--

mir-84 (C.e.; 2)           TGAGGTAGTATGTAATATTGTA--

mir-98 (H.s.; 5)           TGAGGTAGTAAGTTGTATTGTT—

 

 

Cluster 2

 

mir-29a (M.m.; 4)         CTAGCACCATCTGAAATCGGTT--

mir-29 (H.s.; 3)          CTAGCACCATCTGAAATCGGTT--

mir-29c/ (M.m.; 4)        -TAGCACCATTTGAAATCGGTTA-

mir-29b/mir-102 (M.m.; 4) -TAGCACCATTTGAAATCAGTGTT

mir-102 (H.s.; 5)         -TAGCACCATTTGAAATCAGT---

mir-83 (C.e.; 2)          -TAGCACCATATAAATTCAGTAA-

mir-49 (C.e.; 2)          -AAGCACCACGAGAAGCTGCAGA-

 

 

Cluster 3

 

mir-200b (M.m./H.s.; 6) ---TAATACTGCCTGGTAATGATGAC--

mir-141 (M.m.; 4)       ----AACACTGTCTGGTAAAGATGG---

mir-200a (M.m./H.s.; 6) ---TAACACTGTCTGGTAACGATG----

mir-8 (D.m.; 3)         ---TAATACTGTCAGGTAAAGATGTC--

mir-236                 ATCTAATACTGTCAGGTAATGACGCTGG

 

 

Cluster 4

 

mir-72 (C.e.; 1)        AGGCAAGATGTTGGCATAGC--

mir-72 (C.e.; 2)        AGGCAAGATGTTGGCATAGC--

mir-31 (H.s.; 3)        -GGCAAGATGCTGGCATAGCTG

cp-mir-266              AGGCAAGACTTTGGCAAAGC--

cp-mir-269              -GGCAAGACTCTGGCAAAACT-

 

 

Cluster 5

 

mir-99a/mir-99 (M.m.; 4)  --ACCCGTAGATCCGATCT-TGT--

mir-99 (H.s.; 5)          -AACCCGTAGATCCGATCT-TGTG-

mir-100 (H.s.; 5)         -AACCCGTAGATCCGAACT-TGTG-

mir-10 (D.m.; 3)          -ACCCTGTAGATCCGAATT-TGT--

mir-57 (C.e.; 2)          TACCCTGTAGATC-GAGCTGTGTGT

mir-99b (M.m.; 4)         -CACCCGTAGAACCGACCT-TGCG-

mir-51 (C.e.; 2)          -TACCCGTAGCTCCTATCCATGTT-

 

 

Cluster 6

 

mir-103 (H.s.; 5)           -AGCAGCATTGTACAGGGCTATGA

mir-107 (H.s.; 5)           -AGCAGCATTGTACAGGGCTATCA

mir-15a (M.m.; 4)           TAGCAGCA-CATAATGGTTTGTG

mir-15 (H.s.; 3)            TAGCAGCA-CATAATGGTTTGTG

mir-15b (M.m.; 4)           TAGCAGCA-CATCATGGTTTACA

mir-16 (H.s.; 3)            TAGCAGCA-CGTAAATATTGGCG

mir-16 (H.s.; 5)            TAGCAGCA-CGTAAATATTGGCG

mir-16 (M.m.; 4)            TAGCAGCA-CGTAAATATTGGCG

mir-114 (H.s.; 5)           TAGCTGCA-CGTAAATATTGGCG

mir-195 (M.m./H.s.; 6)      TAGCAGCA-CAGAAATATTGGC-

 

 

Cluster 7

 

mir-52 (C.e.; 2)          CACCCGTACATATGTTTCCG-TGCT--

mir-53 (C.e.; 2)          CACCCGTACATTTGTTTCCG-TGCT--

mir-52 (C.e.; 1)          CACCCGTACATATGTTTCCG-TGC---

mir-56_1 (C.e.; 2)        TACCCGTA---ATGTTTCCGCTGAG--

mir-55 (C.e.; 2)          TACCCGTAT--AAGTTTCTGCTGAG--

cp-mir-267                --CCCGTG---AAGTGTCTGCTGCA--

cp-mir-223                TGCCCGTA---CTGTGTCGGCTG----

mir-54 (C.e.; 2)          TACCCGTA---ATCTTCATAATCCGAG

 

 

Cluster 8

 

mir-58 (C.e.; 1)       -TGA-GATCGTTCAGTACGG-C----

mir-58 (C.e.; 2)       -TGA-GATCGTTCAGTACGG-CAAT-

mir-24 (H.s.; 3)       -TGG-CTCAGTTCAGCAGGAACAG--

mir-24 (H.s.; 5)       -TGG-CTCAGTTCAGCAGGAACAG--

mir-24 (M.m.; 4)       -TGG-CTCAGTTCAGCAGGAACAG--

mir-117 (H.s.; 5)      ----------TTCAGCAGGAACAGTT

mir-116 (H.s.; 5)      TTGATCCTGGCTCAGGACGAACGCTG

 

 

Cluster 9

 

mir-122b (M.m.; 4)        ---TGGAGTGTGACAATGGTGTTTGA--

mir-122a_b (M.m.; 4)      ---TGGAGTGTGACAATGGTGTTTG---

mir-122a (M.m.; 4)        ---TGGAGTGTGACAATGGTGTTTGT--

cp-mir-272                ---TGTAG----GCATGGGTGTTTG---

mir-70 (C.e.; 2)          ---TAATACGT--CGTTGGTGTTTCCAT

mir-78 (C.e.; 2)          ---TGGAG----GCCTGGTTGTTTGTGC

 

 

Cluster 10

 

mir-128 (M.m.; 4)       -TCACAGTGAACCGGTCTCTTTT---

mir-139 (M.m.; 4)       TCTACAGTGCACGTGTCT--------

mir-148 (M.m.; 4)       ---TCAGTGCACTA-CAGAACTTTGT

mir-152 (M.m.; 4)       ---TCAGTGCATGA-CAGAACTTGG-

mir-17 (H.s.; 3)        ACTGCAGTGAAGGCACTTGT----

 

 

Cluster 11

 

mir-175 (M.m./H.s.; 7)   --CAAGTCACTAGTGGTTCCGTTTA

mir-26a (M.m.; 4)        TTCAAGTAATCCAGGATAGGCT

mir-26a (H.s.; 3)        TTCAAGTAATCCAGGATAGGCT

mir-26b (H.s.; 3)        TTCAAGTAATTCAGGATAGGTT

mir-26b (M.m.; 4)        TTCAAGTAATTCAGGATAGGTT

 

 

Cluster 12

 

mir-181 (M.m./H.s.; 6)  ---AACATTCAAC-GCTG-TC-GGTGAGT-

mir-178 (M.m./H.s.; 7)  ---AACATTCAAC-GCTG-TC-GGTGAGTT

mir-89 (C.e.; 1)        ---AACACTCAATTTCCAATCAAATAAA--

mir-194 (M.m./H.s.; 6)  TGTAACAG-CAAC-TCCA-T---GTGGA--

mir-132 (M.m.; 4)       --TAACAGTCTACAGCCA-T--GGTC-GT-

 

 

Cluster 13

 

mir-19b (H.s.; 3)      TGTGCAAATCCATGCAAAACTGA

mir-19b (H.s.; 5)      TGTGCAAATCCATGCAAAACTGA

mir-19b (M.m.; 4)      TGTGCAAATCCATGCAAAACTGA

mir-19a (H.s.; 3)      TGTGCAAATCTATGCAAAACTGA

mir-111 (H.s.; 5)      TGTGCAAATCTATGCAAAACTGT

mir-19a (H.s.; 5)      TGTGCAAATCTATGCAAAACTGA

mir-153 (M.m.; 4)      -TTGCATAGTCA--CAAAAGTGA

 

 

Cluster 14

 

mir-2 (C.e.; 1)       -----TATCACAGCCAGCTTTGATGTGC---

mir-2 (C.e.; 2)       -----TATCACAGCCAGCTTTGATGTGC---

mir-13a (D.m.; 3)     -----TATCACAGCCA-TTTTGACGAGT---

mir-13b (D.m.; 3)     -----TATCACAGCCA-TTTTGATGAGT---

mir-2a (D.m.; 3)      -----TATCACAGCCAGCTTTGATGAGC---

mir-2b (D.m.; 3)      -----TATCACAGCCAGCTTTGAGGAGC---

mir-27a (M.m.; 4)     ------TTCACAGTG-GCTAAGTTCCGCT-

mir-27 (H.s.; 3)      ------TTCACAGTG-GCTAAGTTCCGCT-

mir-27 (H.s.; 5)      ------TTCACAGTG-GCTAAGTTCC----

mir-27b (M.m.; 4)     ------TTCACAGTG-GCTAAGTTCTG---

mir-11 (D.m.; 3)      -----CATCACAGT---CTGAGTTCTTGC-

mir-6 (D.m.; 3)       -----TATCACAGTG-GCT--GTTCTTTTT

mir-43 (C.e.; 1)      -----TATCACAGTTTACTTGCTGT-----

mir-43 (C.e.; 2)      -----TATCACAGTTTACTTGCTGTCGC--

mir-28 (H.s.; 3)      AAGGAGCTCACAGTCTATTGAG--------

 

 

Cluster 15

 

mir-39 (C.e.; 2)      TCACCGGGTGTAAA-TCAGCTTG

mir-40 (C.e.; 2)      TCACCGGGTGTACA-TCAGCTAA

mir-41 (C.e.; 2)      TCACCGGGTGAAAAATCACCTA-

mir-36 (C.e.; 2)      TCACCGGGTGAAAATTCGCATG-

mir-35 (C.e.; 2)      TCACCGGGTGGAAACTAGCAGT-

mir-37 (C.e.; 2)      TCACCGGGTGAACACTTGCAGT-

mir-38 (C.e.; 2)      TCACCGGGAGAAAAACTGGAGT-

mir-42 (C.e.; 1)      TCACCGGGTTAACATCTAC----

mir-42 (C.e.; 2)      -CACCGGGTTAACATCTACAG--

 

 

Cluster 16

 

mir-79 (C.e.; 2)       ATAAAGCTAGGTTACCAAAGCT-

mir-131 (M.m.; 4)      -TAAAGCTAGATAACCGAAAGT-

mir-4 (D.m.; 3)        ATAAAGCTAGACAACCATTGA--

mir-75 (C.e.; 2)       TTAAAGCTAC-CAACCGGCTTCA

 

 

Cluster 17

 

mir-23a (M.m.; 4)       ATCACATTGCCAGGGATTTCC-----

mir-23 (H.s.; 3)        ATCACATTGCCAGGGATTTCC-----

mir-23 (H.s.; 5)        ATCACATTGCCAGGGATTTCCA----

mir-23b (M.m.; 4)       ATCACATTGCCAGGGATTACCAC---

mir-119 (H.s.; 5)       -----ATTGCCAGGGATTACCAT---

mir-181 (M.m./H.s.; 7)  ------GTGCTAGGGATTGGGGCTTG

 

 

Cluster 18

 

mir-94 (H.s.; 5)        -AAAGTGCTGACAGTGCAGAT---

mir-195 (M.m./H.s.; 7)  CAAAGTGCTGACAGTTCAGGTAG-

mir-91 (H.s.; 5)        CAAAGTGCTTACAGTGCAGGTAGT

mir-106 (H.s.; 5)       AAAAGTGCTTACAGTGCAGGTAGC

mir-182a (M.m./H.s.; 7) CAAAGTGCTGTTAGTGCAGGTAG-

mir-182b (M.m./H.s.; 7) CAAAGTGCTGTTATTGCAGG----

mir-93 (H.s.; 5)        -AAAGTGCTGTTCGTGCAGGTAG-

mir-20 (M.m.; 4)        TAAAGTGCTTATAGTGCAGGTAG-

mir-20 (H.s.; 3)        TAAAGTGCTTATAGTGCAGGTA--

mir-18 (M.m.; 4)        TAAGGTGCATCTAGTGCAGATA--

mir-18 (H.s.; 5)        TAAGGTGCATCTAGTGCAGAT---

mir-18 (H.s.; 3)        TAAGGTGCATCTAGTGCAGATA--

 

 

Cluster 19

 

mir-73 (C.e.; 2)        TGGCAAGATGTAG--GCAGTTCAGT--

cp-mir-268              -GGCAAGAATTAGAAGCAGTTTGGT--

mir-74 (C.e.; 2)        TGGCAAGAAATGG---CAGTCTACA--

 

Cluster 20

 

lin-4 (C.e.; 2)         TCCCTGAGACC--TCAAGT-GTGA

mir-125b (M.m.; 4)      TCCCTGAGACC--CTAACTTGTGA

mir-125a (M.m.; 4)      TCCCTGAGACCCTTTAACCTGTG-

 

 

Cluster 21

 

mir-64 (C.e.; 2)          TATGACAC-TGAAGCGTTACCGAA-

mir-65 (C.e.; 2)          TATGACAC-TGAAGCGTAACCGAA-

mir-63 (C.e.; 2)          TATGACAC-TGAAGCGAGTTGGAAA

mir-66 (C.e.; 2)          CATGACAC-TGATTAGGGATGTGA-

mir-192 (M.m./H.s.; 6)    -CTGACCTATGAATTGACA------

 

 

Cluster 22

 

mir-62 (C.e.; 1)        TGATATGTAATCTAGCT-TAC--

mir-62 (C.e.; 2)        TGATATGTAATCTAGCT-TACAG

mir-9 (M.m.; 4)         TCTTTGGTTATCTAGCTGTATGA

mir-9 (D.m.; 3)         TCTTTGGTTATCTAGCTGTATGA

 

 

Cluster 23

 

 

mir-1 (C.e.; 1)         TGGAATGTAAAGAAGTATG----

mir-1 (D.m.; 3)         TGGAATGTAAAGAAGTATGGAG-

mir-1 (C.e.; 2)         TGGAATGTAAAGAAGTATGTA--

mir-1d (M.m.; 4)        TGGAATGTAAAGAAGTATGTATT

mir-1c (M.m.; 4)        TGGAATGTAAAGAAGTATGTAC-

mir-1b (M.m.; 4)        TGGAATGTAAAGAAGTATGTAA-

mir-206 (M.m./H.s.; 6)  TGGAATGTAAGGAAGTGTGTGG-

 

 

Cluster 24

 

mir-30a-asb (M.m.; 4)   --------CTT-TCAGTCGGATGTTTGCAGC

mir-30 (H.s.; 3)        --------CTT-TCAGTCGGATGTTTGCAGC

mir-21 (H.s.; 3)        -----TAGCTTATCAGACTGATGTTGA----

mir-21 (H.s.; 5)        -----TAGCTTATCAGACTGATGTTGAC---

mir-21 (M.m.; 4)        -----TAGCTTATCAGACTGATGTTGA----

mir-59 (C.e.; 2)        TCGAATCGTTTATCAGGATGATG--------

 

 

Cluster 25

 

mir-30b (M.m.; 4)          TGTAAACATCCTACACTC--AGC

mir-30c (M.m.; 4)          TGTAAACATCCTACACTCTCAGC

mir-30a-s/mir-97 (M.m.; 4) TGTAAACATCCTCGACTGGAAGC

mir-97 (H.s.; 5)           TGTAAACATCCTCGACTGGAAGC

mir-30d (M.m.; 4)          TGTAAACATCCCCGACTGGAAG-

 

 

Cluster 26

 

mir-183 (M.m./H.s.; 6)  ---TATGGCACTGGTAGAATTCACTG-

mir-174 (M.m./H.s.; 7)  ---TATGGCACTGGTAGAATTCACT--

mir-182 (M.m./H.s.; 6)  ---TTTGGCAATGGTAGAACTCACA--

mir-228                 ---AATGGCACTGCATGAATTCACGGC

mir-263                 GTTAATGGCACTGGAAGAATTCAC---

 

 

Cluster 27

 

mir-123 (M.m.; 4)       -CATTATTACTTTTGG-TACGCG---

mir-137 (M.m.; 4)       ----TATTGCTTAAGAATACGCGTAG

mir-12 (D.m.; 3)        TGAGTATTACATCAGG-TACTGGT--

 

 

Cluster 28

 

mir-50 (C.e.; 2)        TGATATGTCTGGTATTCTTGGGTT-

mir-190 (M.m./H.s.; 6)  TGATATGTTTGATATA-TTAGGT--

mir-90 (C.e.; 1)        TGATATGTT--GTTTGAATGCCCC-

 

 

Cluster 29

 

mir-196b (M.m./H.s.; 7)      TAAGGGCTGGGTCGGTCGGGCT

mir-196c (M.m./H.s.; 7)      ---GGGCTGGG-CGGTCGGGC-

mir-196a (M.m./H.s.; 7)      TAAGGGCTGGGCCGGTCGGGCT

 

 

Cluster 30

 

mir-208 (M.m./H.s.; 6)    --ATAAGACGAGCAAAAAGCTTGT

mir-184 (M.m./H.s.; 7)    ATGCAAGTCGAGCTTGAAGTTTC-

 

 

Cluster 31

 

mir-155 (M.m.; 4)      ---TTAATGCTAATTGTGATAGGGG

mir-5 (D.m.; 3)        AAAGGAACGATCGTTGTGATATG--

 

 

Cluster 32

 

mir-196 (M.m./H.s.; 6)     -TAGGTAG--T---TTCATGTTGTTGG

mir-48 (C.e.; 2)           TGAGGTAGGCTCAGTAGATGCGA----

 

 

Cluster 33

 

mir-77 (C.e.; 2)            TTCATCAGGCCATAGCTGTCCA

mir-176 (M.m./H.s.; 7)      ---GGACTGCCTCAGCTGTGC-

 

 

Cluster 34

 

mir-86 (C.e.; 2)       ---TAAGTGAATGCTT-TGCCACAGTC

mir-147 (M.m.; 4)      GTGTGTGGAAATGCTTCTGCC------

 

 

Cluster 35

 

mir-190 (M.m./H.s.; 7)   TACCGCATAATGTTGAAAG-ATGG----

mir-192 (M.m./H.s.; 7)   ------ATAACGTTGAAAG-ATGGCATC

mir-142-s (M.m.; 4)      -----CATAAAGTAGAAAGCACTAC---

 

 

Cluster 36

 

mir-46 (C.e.; 2)          TGTCATGGAGTCGCTCTCTTCA

mir-47 (C.e.; 2)          TGTCATGGAGGCGCTCTCTTCA

 

 

Cluster 37

 

mir-44 (C.e.; 2)      TGACTAGAGACAC-ATTCAGCT

mir-61 (C.e.; 2)      TGACTAGAACCGTTACTCATC-

 

 

Cluster 38

 

mir-68 (C.e.; 2)          TCGAAGACTC---AAAAGTGTAGA

mir-69 (C.e.; 2)          TCGAAAATTA---AAAAGTGTAGA

mir-67 (C.e.; 2)          TCACAACCTCCTAGAAAGAGTAGA

 

 

Cluster 39

 

mir-3 (D.m.; 3)         TCACTGGGCAAAGTGTGTCTCA-

mir-87 (C.e.; 1)        ---GTGAGCAAAGTTTCAGGTGT

 

 

Cluster 40

 

mir-105 (H.s.; 5)                  TCAAATGCTCAGACT-CCTGT-

mir-199-s (M.m./H.s.; 6)      CCCAGTGTTCAGACTACCTGTT

 

 

Cluster 41

 

mir-88 (C.e.; 1)       ---TCTTTGACGTCGGGACTGGAG

mir-186 (M.m./H.s.; 7) CGGCCTTAGTCGTCGGGG-TGATT

 

 

Cluster 42

 

mir-95 (H.s.; 5)      TTCAACGGGTATTTATTGAGCA--

cp-mir-264            ---GGCGGGTGGTTGTTGT-TATG