Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.107614
Description:DKFZP564I1171 protein
Best-Of-UniGene (BOU) SequenceAK023178
Genomic Coordiantes Displayed:Bases 612200 to 624800 of contig Hs5_17022_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.107614.jpeg
Best sense EST/protein match:BF313393 matched pir||T17300 hypothetical protein DKFZp564I1171.1 - human (fragment) (E = 3e-78)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AI921998 cDNA clone IMAGE:2452814 uterus 3' read Protein similarity
  AW078949 cDNA clone IMAGE:2576847 2 pooled wilms' tumors, one primary and one metastatic to 3' read Protein similarity
  BF197874 cDNA clone IMAGE:3652633 skin, normal, 4 pooled samples 3' read Protein similarity
  BE348965 cDNA clone IMAGE:3149842 malignant melanoma, metastatic to lymph node 3' read Protein similarity
  R55816 cDNA clone IMAGE:41016 brain 3' read 1.3 kbProtein similarity
  R55741 cDNA clone IMAGE:40614 brain 3' read 1.4 kbProtein similarity
  R52623 cDNA clone IMAGE:39898 brain 3' read 1.3 kbProtein similarity
  R42071 cDNA clone IMAGE:30746 brain 3' read 1.4 kbProtein similarity
  R41709 cDNA clone IMAGE:30529 brain 3' read 1.4 kbProtein similarity
  R41531 cDNA clone IMAGE:30604 brain 3' read 1.4 kbProtein similarity
  R41342 cDNA clone IMAGE:30362 brain 3' read 1.3 kbProtein similarity
  R39807 cDNA clone IMAGE:26496 brain 3' read 1.4 kbProtein similarity
  H07934 cDNA clone IMAGE:45587 brain 3' read 1.4 kbProtein similarity
  F01990 cDNA clone c0kh03 brain 3' read Protein similarity
  Z41511 cDNA clone czwf01 brain 3' read Protein similarity
  F04502 cDNA clone czpd01 brain 3' read Protein similarity
  T16796 cDNA clone NIB1867 brain 3' read Protein similarity
  F04283 cDNA clone c2og03 brain 3' read Protein similarity
  F02418 cDNA clone c0yg03 brain 3' read Protein similarity
  R61513 cDNA clone IMAGE:37790 brain 3' read Protein similarity
  R56062 cDNA clone IMAGE:40987 brain 3' read 1.3 kbProtein similarity
  AA583775 cDNA clone IMAGE:1088179 larynx 3' read 0.5 kbProtein similarity
  BG741009 cDNA clone IMAGE:4779656 skin 5' read Protein similarity
  R56174 cDNA clone IMAGE:40987 brain 5' read 1.3 kb
  H08040 cDNA clone IMAGE:45587 brain 5' read 1.4 kb
  R53277 cDNA clone IMAGE:39898 brain 5' read 1.3 kb
  R55901 cDNA clone IMAGE:41016 brain 5' read 1.3 kb
  R18693 cDNA clone IMAGE:30746 brain 5' read 1.4 kb
  H14874 cDNA clone IMAGE:48816 brain 5' read 1.4 kb
  R55726 cDNA clone IMAGE:40614 brain 5' read 1.4 kb
  R18545 cDNA clone IMAGE:30604 brain 5' read 1.4 kb
  R18163 cDNA clone IMAGE:30529 brain 5' read 1.4 kb
  R12760 cDNA clone IMAGE:26496 brain 5' read 1.4 kb
  T78296 cDNA clone IMAGE:24141 brain 5' read 1.4 kb
  R61569 cDNA clone IMAGE:37790 brain 5' read
  F08538 cDNA clone czwf01 brain 5' read
  R18494 cDNA clone IMAGE:30362 brain 5' read 1.3 kb
  F08274 cDNA clone czpd01 brain 5' read
  F05741 cDNA clone c0kh03 brain 5' read
  F08044 cDNA clone c2og03 brain 5' read
  F06146 cDNA clone c0yg03 brain 5' read

SENSE ESTs

  BI911282 cDNA clone IMAGE:5212173 leukocyte 5' read Protein similarity
  BE783756 cDNA clone IMAGE:3874215 retinoblastoma 5' read
  BI820493 cDNA clone IMAGE:5177093 pooled brain, lung, testis 5' read Protein similarity