Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.155983
Description:KIAA0677 gene product
Best-Of-UniGene (BOU) SequenceNM_014663
Genomic Coordiantes Displayed:Bases 2670000 to 2880000 of contig Hs1_5009_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.155983.jpeg
Best sense EST/protein match:BE249964 matched ref|NP_055478.1| (NM_014663) KIAA0677 gene product [Homo sapiens] (E = e-115)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BM051671 cDNA clone IMAGE:5419546 burkitt lymphoma 5' read
  BE269084 cDNA clone IMAGE:3542242 burkitt lymphoma 5' read
  BE267516 cDNA clone IMAGE:2989303 burkitt lymphoma 5' read
  BI226856 cDNA clone IMAGE:5096077 burkitt lymphoma 5' read
  BE398095 cDNA clone IMAGE:3620713 burkitt lymphoma 5' read
  BI226779 cDNA clone IMAGE:5096101 burkitt lymphoma 5' read Protein similarity
  BE397950 cDNA clone IMAGE:3620851 burkitt lymphoma 5' read
  BE398137 cDNA clone IMAGE:3620635 burkitt lymphoma 5' read
  BE267717 cDNA clone IMAGE:2989444 burkitt lymphoma 5' read

SENSE ESTs

  BE903569 cDNA clone IMAGE:3960164 choriocarcinoma 5' read Protein similarity
  BE900592 cDNA clone IMAGE:3956586 choriocarcinoma 5' read Protein similarity
  BE280869 cDNA clone IMAGE:3138875 choriocarcinoma 5' read Protein similarity
  AV709306 cDNA clone ADCAUD09 adrenal gland 5' read Protein similarity
  BE867043 cDNA clone IMAGE:3847027 adenocarcinoma 5' read
  BG911641 cDNA clone IMAGE:4940016 anaplastic oligodendroglioma with 1p/19q loss 5' read
  BG323373 cDNA clone IMAGE:4559680 renal cell adenocarcinoma 5' read Protein similarity
  BG325116 cDNA clone IMAGE:4561457 renal cell adenocarcinoma 5' read Protein similarity
  BG327482 cDNA clone IMAGE:4564479 renal cell adenocarcinoma 5' read Protein similarity
  BE249964 cDNA clone IMAGE:2959638 adenocarcinoma cell line 5' read Protein similarity
  BE885470 cDNA clone IMAGE:3909087 leiomyosarcoma 5' read Protein similarity
  BE305118 cDNA clone IMAGE:2959638 adenocarcinoma cell line 5' read Protein similarity
  BG828170 cDNA clone IMAGE:4906094 rhabdomyosarcoma 5' read Protein similarity
  BG395807 cDNA clone IMAGE:4581140 retinoblastoma 5' read Protein similarity
  BG035010 cDNA clone IMAGE:4413357 adenocarcinoma, cell line 5' read Protein similarity
  BE252880 cDNA clone IMAGE:3358174 retinoblastoma 5' read Protein similarity
  BE780387 cDNA clone IMAGE:3872114 retinoblastoma 5' read Protein similarity
  BE293009 cDNA clone IMAGE:3349398 adenocarcinoma cell line 5' read Protein similarity
  BM047618 cDNA clone IMAGE:5457350 carcinoma, cell line 5' read
  BI820812 cDNA clone IMAGE:5175389 pooled brain, lung, testis 5' read Protein similarity
  BG574537 cDNA clone IMAGE:4705106 mammary adenocarcinoma, cell line 5' read Protein similarity
  BG179170 cDNA clone IMAGE:4431491 adenocarcinoma, cell line 5' read Protein similarity
  AA160471 cDNA clone IMAGE:592563 5' read 1.0 kbProtein similarity
  BE794777 cDNA clone IMAGE:3943541 small cell carcinoma 5' read Protein similarity
  BF339879 cDNA clone IMAGE:4186702 glioblastoma with egfr amplification 5' read Protein similarity
  AA160515 cDNA clone IMAGE:592563 3' read 1.0 kbProtein similarity
  BF237665 cDNA clone IMAGE:4079602 leiomyosarcoma cell line 5' read Protein similarity
  BE886069 cDNA clone IMAGE:3909222 leiomyosarcoma 5' read
  AL039988 cDNA clone DKFZp434L2212 testis 5' read Protein similarity
  T61636 cDNA clone IMAGE:78136 liver 3' read
  BI869827 cDNA clone IMAGE:5403371 adenocarcinoma, cell line 5' read
  BI192555 cDNA clone IMAGE:5088757 epithelioid carcinoma cell line 5' read
  BE871201 cDNA clone IMAGE:3852907 adenocarcinoma 5' read
  AL079363 cDNA clone DKFZp564P1972 brain 5' read
  BG494253 cDNA clone IMAGE:4672415 mucoepidermoid carcinoma 5' read