Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.268744
Description:KIAA1796 protein
Best-Of-UniGene (BOU) SequenceAB058699
Genomic Coordiantes Displayed:Bases 2132335 to 2241309 of contig Hs10_8999_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.268744.jpeg
Best sense EST/protein match:BG572048 matched gb|AAH11268.1|AAH11268 (BC011268) Similar to KIAA0273 gene product [Homo sapiens] (E = e-105)
Best antisense EST/protein match:BF575482 matched dbj|BAB23571.1| (AK004797) data source:SPTR, source key:Q99787, (E = 1e-64)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BG707682 cDNA clone IMAGE:4793154 hypothalamus, cell line 5' read
  AI453702 cDNA clone IMAGE:2143874 pancreas 3' read 0.5 kbPolyadenylation signal
  AI362528 cDNA clone IMAGE:1979936 stomach 3' read Polyadenylation signal
  N64328 cDNA clone IMAGE:286126 ear 3' read Polyadenylation signal
  BF693234 cDNA clone IMAGE:4245461 muscle (skeletal) 5' read
  D62629 cDNA clone GEN308B09 aorta 5' read
  BI670308 cDNA clone IMAGE:5314337 hypothalamus, cell line 5' read
  BF670071 cDNA clone IMAGE:4275479 primitive neuroectoderm 5' read
  BF574920 cDNA clone IMAGE:4289701 muscle (skeletal) 5' read
  AV725275 cDNA clone HTCCBC03 hypothalamus 5' read
  BF696434 cDNA clone IMAGE:4282222 primitive neuroectoderm 5' read
  AV727971 cDNA clone HTCAKE11 hypothalamus 5' read
  BF575482 cDNA clone IMAGE:4288471 muscle (skeletal) 5' read

SENSE ESTs

  BI550687 cDNA clone IMAGE:5275575 hippocampus, cell line 5' read Protein similarity
  BI603513 cDNA clone IMAGE:5286938 hypothalamus, cell line 5' read Protein similarity
  BI546122 cDNA clone IMAGE:5259839 hippocampus, cell line 5' read Protein similarity
  BI599661 cDNA clone IMAGE:5299478 hypothalamus, cell line 5' read Protein similarity
  BG709415 cDNA clone IMAGE:4796390 hypothalamus, cell line 5' read Protein similarity
  BI821865 cDNA clone IMAGE:5176909 pooled brain, lung, testis 5' read Protein similarity
  AA305419 cDNA clone ATCC:128949 5' read
  BG699147 cDNA clone IMAGE:4811569 hippocampus, cell line 5' read Protein similarity
  BI771102 cDNA clone IMAGE:5209051 pooled lung and spleen 5' read Protein similarity
  BG912062 cDNA clone IMAGE:4942300 anaplastic oligodendroglioma with 1p/19q loss 5' read Protein similarity
  BI758797 cDNA clone IMAGE:5183448 pooled colon, kidney, stomach 5' read Protein similarity
  D81446 cDNA clone GEN165A06 brain 5' read
  BF346791 cDNA clone IMAGE:4156912 anaplastic oligodendroglioma with 1p/19q loss 5' read Protein similarity
  BG720412 cDNA clone IMAGE:4823858 testis, cell line 5' read
  BI458226 cDNA clone IMAGE:5278385 hypothalamus, cell line 5' read Protein similarity
  BI601115 cDNA clone IMAGE:5301147 hypothalamus, cell line 5' read Protein similarity
  BI601032 cDNA clone IMAGE:5301122 hypothalamus, cell line 5' read Protein similarity
  BI602588 cDNA clone IMAGE:5300474 hypothalamus, cell line 5' read Protein similarity
  BI600590 cDNA clone IMAGE:5287193 hypothalamus, cell line 5' read Protein similarity
  AA379840 cDNA clone ATCC:184223 skin 5' read Protein similarity
  AW958395 cDNA clone (no-name) Protein similarity
  BG401924 cDNA clone IMAGE:4594711 kidney 5' read
  D81295 cDNA clone GEN144D03 brain 5' read Protein similarity
  BG719971 cDNA clone IMAGE:4823430 testis, cell line 5' read Protein similarity
  AI927768 cDNA clone IMAGE:2454775 pancreas 3' read Protein similarity
  AI927757 cDNA clone IMAGE:2454774 pancreas 3' read Protein similarity
  AI927758 cDNA clone IMAGE:2454776 pancreas 3' read Protein similarity
  Z43289 cDNA clone c18b08 brain Protein similarity
  BG572048 cDNA clone IMAGE:4719986 placenta 5' read Protein similarity
  T78758 cDNA clone IMAGE:24280 brain 5' read 1.7 kbProtein similarity
  Z44077 cDNA clone c1rh06 brain Protein similarity
  R18887 cDNA clone IMAGE:27164 brain 5' read 1.3 kbProtein similarity
  H15885 cDNA clone IMAGE:48848 brain 5' read 1.3 kbProtein similarity
  AA318875 cDNA clone ATCC:119448 adrenal gland 5' read
  BE778633 cDNA clone IMAGE:3869156 retinoblastoma 5' read
  BI828105 cDNA clone IMAGE:5167215 medulla 5' read