Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.27379
Description:ESTs
Best-Of-UniGene (BOU) SequenceAL041761
Genomic Coordiantes Displayed:Bases 1224503 to 1232262 of contig Hs1_4581_24
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingHs.27379.jpeg
Best sense EST/protein match:No protein match with an e-value of less than 1e-10
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AV739101 cDNA clone CBMAPC01 cord blood 5' read
  H17455 cDNA clone IMAGE:50060 brain 3' read 2.0 kbPolyadenylation signal
  AI523138 cDNA clone IMAGE:2127827 aorta 3' read Polyadenylation signal
  F03269 cDNA clone c1rg05 brain 3' read
  AW083485 cDNA clone IMAGE:2583727 moderately differentiated adenocarcinoma 3' read
  Z39428 cDNA clone c19h06 brain 3' read
  AL041760 cDNA clone DKFZp434A0118 testis 5' read