Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Hs.4082
Description:lectin, galactoside-binding, soluble, 8 (galectin 8)
Best-Of-UniGene (BOU) SequenceL78132
Genomic Coordiantes Displayed:Bases 2431856 to 2478030 of contig Hs1_4993_24
BOU Orientation Along Contig:RIGHT-TO-LEFT with respect to contig
Link to JPEG of genomic mappingHs.4082.jpeg
Best sense EST/protein match:BG831730 matched gb|AAF19370.1| (AF193806) galectin-8 [Homo sapiens] (E = e-109)
Best antisense EST/protein match:No protein match with an e-value of less than 1e-10


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  AA294880 cDNA clone ATCC:190376 pancreas 5' read Protein similarity
  AW630092 cDNA clone IMAGE:2968885 2 pooled high-grade transitional cell tumors 5' read
  AA707060 cDNA clone IMAGE:452005 pool 3' read
  BF793632 cDNA clone IMAGE:4346595 adrenal cortex carcinoma, cell line 5' read
  BE392632 cDNA clone IMAGE:3625526 endometrium, adenocarcinoma cell line 5' read
  BF971426 cDNA clone IMAGE:4361314 adrenal cortex carcinoma, cell line 5' read
  W87890 cDNA clone IMAGE:417035 pool 5' read 0.6 kb
  BG251759 cDNA clone IMAGE:4472294 adenocarcinoma, cell line 5' read
  AI625641 cDNA clone IMAGE:2283280 uterus 3' read 2.1 kb
  AV691368 cDNA clone GKCDZD07 hepatocellular carcinoma 5' read
  W87817 cDNA clone IMAGE:417035 pool 3' read 0.6 kb
  AW613828 cDNA clone IMAGE:2968885 2 pooled high-grade transitional cell tumors 3' read
  BF476642 cDNA clone IMAGE:4091509 sympathetic trunk 3' read
  BI495923 cDNA clone IMAGE:2540296 ear 5' read
  BI495922 cDNA clone IMAGE:2540296 ear 3' read
  AW473245 cDNA clone IMAGE:2853111 uterus 3' read
  BF341120 cDNA clone IMAGE:4186161 glioblastoma with egfr amplification 5' read
  W86887 cDNA clone IMAGE:416451 pool 3' read
  AA682555 cDNA clone IMAGE:431270 pool 3' read Protein similarityPolyadenylation signal
  D60548 cDNA clone GEN116B10 brain 3' read Protein similarity

SENSE ESTs

  AV756081 cDNA clone BMFAZG01 bone marrow 5' read
  F13139 cDNA clone c3jc12 brain
  AV687748 cDNA clone GKCFHG11 hepatocellular carcinoma 5' read
  AV757382 cDNA clone BMFAZA05 bone marrow 5' read
  AI241431 cDNA clone IMAGE:1850919 pool 3' read 1.0 kb
  AI354644 cDNA clone IMAGE:1979809 stomach 3' read 1.3 kbProtein similarity
  AI589251 cDNA clone IMAGE:2222492 pancreas 3' read 1.8 kb
  AI679874 cDNA clone IMAGE:2256055 stomach 3' read 1.0 kb
  AA846111 cDNA clone IMAGE:1414518 spleen 3' read Protein similarity
  AI679297 cDNA clone IMAGE:2255671 stomach 3' read 1.0 kb
  AI679893 cDNA clone IMAGE:2256079 stomach 3' read 4.2 kbPolyadenylation signal
  AI679384 cDNA clone IMAGE:2255695 stomach 3' read 0.8 kbPolyadenylation signal
  D31290 cDNA clone (no-name) lung 5' read
  BF172028 cDNA clone (no-name) blood
  AV686276 cDNA clone GKCDUD05 hepatocellular carcinoma 5' read
  BI916024 cDNA clone IMAGE:5248690 brain 5' read
  BG403136 cDNA clone IMAGE:4525982 transitional cell papilloma, cell line 5' read
  BE906432 cDNA clone IMAGE:3904025 epithelioid carcinoma 5' read
  R55562 cDNA clone IMAGE:40272 brain 5' read 1.8 kb
  AV690848 cDNA clone GKCDFG02 hepatocellular carcinoma 5' read
  AA703495 cDNA clone IMAGE:450011 pool 3' read
  AA374792 cDNA clone ATCC:179218 5' read
  AW273675 cDNA clone IMAGE:2818548 two pooled squamous cell carcinomas 3' read Polyadenylation signal
  AA595981 cDNA clone IMAGE:1088873 larynx 3' read 1.4 kb
  AU136490 cDNA clone PLACE1004382 placenta 5' read
  Z41492 cDNA clone czvh01 brain 3' read Polyadenylation signal
  W90691 cDNA clone IMAGE:418280 pool 3' read 1.1 kbPolyadenylation signal
  AV708724 cDNA clone ADCACE10 adrenal gland 5' read
  AI249371 cDNA clone IMAGE:2005101 pancreas 3' read 0.4 kbPolyadenylation signal
  AA310776 cDNA clone ATCC:156781 5' read
  AI832987 cDNA clone IMAGE:2376834 colon 3' read Polyadenylation signal
  AU155954 cDNA clone PLACE1001701 placenta 3' read Polyadenylation signal
  H29785 cDNA clone IMAGE:52757 brain 3' read 1.5 kbPolyadenylation signal
  AU138661 cDNA clone PLACE1009037 placenta 5' read
  AW304718 cDNA clone IMAGE:2826157 three pooled meningiomas 3' read
  AA357945 cDNA clone ATCC:162302 lung 5' read
  BG286430 cDNA clone IMAGE:4500555 transitional cell papilloma, cell line 5' read
  AA355630 cDNA clone ATCC:157755 5' read
  AV726181 cDNA clone HTCBNB08 hypothalamus 5' read
  W90786 cDNA clone IMAGE:418280 pool 5' read 1.1 kb
  AA337085 cDNA clone ATCC:138875 uterus 5' read
  F08504 cDNA clone czvh01 brain 5' read Protein similarity
  AA885888 cDNA clone IMAGE:1492582 kidney 3' read
  AI697322 cDNA clone IMAGE:2208156 uterus 3' read 0.9 kbProtein similarity
  BG178647 cDNA clone IMAGE:4430021 adenocarcinoma, cell line 5' read Protein similarity
  BE871342 cDNA clone IMAGE:3853430 adenocarcinoma 5' read Protein similarity
  BG331516 cDNA clone IMAGE:4549652 large cell carcinoma 5' read Protein similarity
  BG437687 cDNA clone IMAGE:4621738 large cell carcinoma 5' read Protein similarity
  BG832176 cDNA clone IMAGE:4907504 epithelioid carcinoma cell line 5' read Protein similarity
  BE539116 cDNA clone IMAGE:3448096 placenta 5' read Protein similarity
  AU135298 cDNA clone PLACE1001701 placenta 5' read Protein similarity
  BI758016 cDNA clone IMAGE:5200834 brain 5' read Protein similarity
  AA863226 cDNA clone IMAGE:1455747 kidney 3' read 1.5 kbProtein similarity
  BI829461 cDNA clone IMAGE:5172093 medulla 5' read Protein similarity
  AI076837 cDNA clone IMAGE:1674049 pool 3' read 0.8 kbProtein similarity
  AV728415 cDNA clone HTCADE07 hypothalamus 5' read Protein similarity
  BG109688 cDNA clone IMAGE:4368317 osteosarcoma, cell line 5' read Protein similarity
  BF213535 cDNA clone IMAGE:4070550 from acute myelogenous leukemia 5' read Protein similarity
  AA385876 cDNA clone ATCC:190054 thyroid 5' read Protein similarity
  AA777554 cDNA clone IMAGE:448438 pool 3' read Protein similarity
  BG832253 cDNA clone IMAGE:4907434 epithelioid carcinoma cell line 5' read Protein similarity
  BI524045 cDNA clone IMAGE:5201812 pooled lung and spleen 5' read Protein similarity
  BE895492 cDNA clone IMAGE:3922939 melanotic melanoma 5' read Protein similarity
  BI915727 cDNA clone IMAGE:5248039 brain 5' read Protein similarity
  AV712983 cDNA clone DCAAKF01 5' read Protein similarity
  BG831730 cDNA clone IMAGE:4908006 epithelioid carcinoma cell line 5' read Protein similarity
  BI827040 cDNA clone IMAGE:5167678 medulla 5' read Protein similarity
  BI559939 cDNA clone IMAGE:5295697 testis, cell line 5' read Protein similarity
  AV718043 cDNA clone FHTAABH07 hypothalamus 5' read Protein similarity
  BF244414 cDNA clone IMAGE:4080313 glioblastoma 5' read Protein similarity
  W85928 cDNA clone IMAGE:416156 pool 5' read 1.1 kbProtein similarity
  BI464487 cDNA clone IMAGE:5271304 testis, cell line 5' read Protein similarity
  AV712996 cDNA clone DCAAKF11 5' read Protein similarity
  AU138512 cDNA clone PLACE1008713 placenta 5' read Protein similarity
  BI831607 cDNA clone IMAGE:5166394 medulla 5' read Protein similarity
  BI829002 cDNA clone IMAGE:5166955 medulla 5' read Protein similarity
  BG723129 cDNA clone IMAGE:4823113 testis, cell line 5' read Protein similarity
  BI910272 cDNA clone IMAGE:5217576 leukocyte 5' read Protein similarity
  H29784 cDNA clone IMAGE:52757 brain 5' read 1.5 kbProtein similarity
  BI193693 cDNA clone IMAGE:5089999 epithelioid carcinoma cell line 5' read Protein similarity
  BG717012 cDNA clone IMAGE:4821732 testis, cell line 5' read Protein similarity
  BG829697 cDNA clone IMAGE:4898992 epithelioid carcinoma cell line 5' read Protein similarity
  AV733193 cDNA clone cdAASA12 pheochromocytoma 5' read Protein similarity
  AA361207 cDNA clone ATCC:165339 lymph 5' read Protein similarity
  BI551403 cDNA clone IMAGE:5263784 hippocampus, cell line 5' read Protein similarity
  BI832234 cDNA clone IMAGE:5171602 medulla 5' read Protein similarity
  AU117713 cDNA clone HEMBA1002030 whole embryo, mainly head 5' read Protein similarity
  BG830195 cDNA clone IMAGE:4906723 epithelioid carcinoma cell line 5' read Protein similarity
  BI559345 cDNA clone IMAGE:5295411 testis, cell line 5' read Protein similarity
  BI561928 cDNA clone IMAGE:5297170 testis, cell line 5' read Protein similarity
  AA336989 cDNA clone ATCC:138946 uterus 5' read Protein similarity
  AU099142 cDNA clone HEP21234 Protein similarity
  BE897760 cDNA clone IMAGE:3923237 melanotic melanoma 5' read
  BG433712 cDNA clone IMAGE:4611281 kidney 5' read