Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.182067
Description:inositol polyphosphate-5-phosphatase, 72 kDa
Best-Of-UniGene (BOU) SequenceNM_033134
Genomic Coordiantes Displayed:Bases 13054000 to 13096000 of contig GA_x5J8B7W4QPD
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingMm.182067.jpeg
Best sense EST/protein match:BG804231 matched ref|NP_149125.1| (NM_033134) inositol polyphosphate-5-phosphatase, 72 kDa [Mus (E = e-111)
Best antisense EST/protein match:AA615877 matched sp|Q9DC61|MPPA_MOUSE MITOCHONDRIAL PROCESSING PEPTIDASE ALPHA SUBUNIT, MITOCHONDRIAL (E = e-106)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BG808251 cDNA clone (no-name) neural retina
  AA982579 cDNA clone IMAGE:1617507 hypothalamus 5' read
  AW212980 cDNA clone IMAGE:2647835 tumor, biopsy sample 3' read Polyadenylation signal
  BG069832 cDNA clone H3080F03 3' read Polyadenylation signal
  AU020871 cDNA clone J0539C05 embryo 3' read Polyadenylation signal
  AW214457 cDNA clone IMAGE:2645786 spontaneous tumor, metastatic to mammary. stem cell origin. 3' read Polyadenylation signal
  AA529277 cDNA clone IMAGE:905745 embryo 5' read
  AV285992 cDNA clone 5031416L06 ovary and uterus
  AA518980 cDNA clone IMAGE:903247 muscle 5' read
  AA796608 cDNA clone IMAGE:1078314 colon 5' read
  BI689856 cDNA clone IMAGE:5356266 infiltrating ductal carcinoma 5' read
  AA793291 cDNA clone IMAGE:990015 embryo 5' read
  AA270970 cDNA clone IMAGE:738046 liver 5' read
  AI182969 cDNA clone IMAGE:1395914 mammary gland 5' read
  AA272103 cDNA clone IMAGE:734037 embryo 5' read
  AA895542 cDNA clone IMAGE:1278721 macrophage 5' read
  AA512548 cDNA clone IMAGE:863812 mammary gland 5' read
  AA755819 cDNA clone IMAGE:1179639 mammary gland 5' read
  BI790063 cDNA clone (no-name) 3' read Protein similarity
  BI467108 cDNA clone (no-name) 3' read
  AI197752 cDNA clone IMAGE:1496500 uterus 5' read
  BF224749 cDNA clone IMAGE:3668666 tumor, gross tissue 3' read Protein similarity
  AA966983 cDNA clone IMAGE:1349050 mammary gland 5' read Protein similarity
  AI156384 cDNA clone IMAGE:1479955 uterus 5' read Protein similarity
  AW542903 cDNA clone C0163C12 3' read Protein similarity
  BG064065 cDNA clone H3015B04 3' read Protein similarity
  AW540449 cDNA clone C0133B07 3' read Protein similarity
  AA275587 cDNA clone IMAGE:766126 kidney 5' read Protein similarity
  BI789862 cDNA clone (no-name) 5' read Protein similarity
  BI441372 cDNA clone (no-name) 5' read Protein similarity
  AI118674 cDNA clone IMAGE:1397804 mammary gland 5' read Protein similarity
  BI986013 cDNA clone (no-name) neural retina
  BI985774 cDNA clone (no-name) neural retina
  AA896797 cDNA clone IMAGE:1295061 macrophage 5' read Protein similarity
  BE287344 cDNA clone IMAGE:3488339 tumor, gross tissue 5' read Protein similarity
  D77863 cDNA clone B1A04 embryonal carcinoma Protein similarity
  AA914088 cDNA clone IMAGE:1313648 mammary gland 5' read Protein similarity
  BF117988 cDNA clone IMAGE:3668666 tumor, gross tissue 5' read Protein similarity
  BE913705 cDNA clone IMAGE:3968966 tumor, biopsy sample 5' read Protein similarity
  BI663437 cDNA clone IMAGE:5321856 infiltrating ductal carcinoma 5' read Protein similarity
  BI732291 cDNA clone IMAGE:5361460 retina 5' read Protein similarity
  BF787749 cDNA clone IMAGE:4241737 kidney 5' read Protein similarity
  BI110277 cDNA clone IMAGE:5030545 tumor, gross tissue 5' read Protein similarity
  BI684840 cDNA clone IMAGE:5343942 infiltrating ductal carcinoma 5' read Protein similarity
  BI732319 cDNA clone IMAGE:5361516 retina 5' read Protein similarity
  BI143606 cDNA clone IMAGE:5064440 kidney 5' read Protein similarity
  AL034709 cDNA clone 528_8N18 dissected endoderm 5' read Protein similarity
  BF536412 cDNA clone IMAGE:4191161 salivary gland 5' read Protein similarity
  AA563248 cDNA clone IMAGE:977978 embryo 5' read Protein similarity
  BE915975 cDNA clone IMAGE:3969400 tumor, biopsy sample 5' read Protein similarity
  AA615877 cDNA clone IMAGE:1066807 mammary gland 5' read Protein similarity
  BI646934 cDNA clone IMAGE:5319045 tumor, gross tissue 5' read Protein similarity
  BF787776 cDNA clone IMAGE:4241697 kidney 5' read Protein similarity
  BI556849 cDNA clone IMAGE:5291540 tumor, gross tissue 5' read Protein similarity
  BF159523 cDNA clone IMAGE:3988133 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  BG808030 cDNA clone (no-name) neural retina
  BE913775 cDNA clone IMAGE:3968939 tumor, biopsy sample 5' read Protein similarity
  AA155273 cDNA clone IMAGE:605485 embryonal carcinoma 5' read Protein similarity
  AL362614 cDNA clone K9129A08 embryo 5' read Protein similarity
  AI604783 cDNA clone IMAGE:387895 embryo 3' read Protein similarityPolyadenylation signal
  W66602 cDNA clone IMAGE:387895 embryo 5' read
  AI430651 cDNA clone IMAGE:387895 embryo 5' read

SENSE ESTs

  BI732508 cDNA clone IMAGE:5362658 retina 5' read
  AW763250 cDNA clone IMAGE:3155643 tumor, gross tissue 5' read
  AA763730 cDNA clone IMAGE:1068172 mammary gland 5' read Protein similarity
  AA763683 cDNA clone IMAGE:1068157 mammary gland 5' read Protein similarity
  AA103185 cDNA clone IMAGE:553880 embryo 5' read Protein similarity
  BG804231 cDNA clone (no-name) neural retina
  BI647387 cDNA clone IMAGE:5319970 tumor, gross tissue 5' read Protein similarity
  BI101541 cDNA clone IMAGE:5042912 kidney 5' read Protein similarity
  BF607748 cDNA clone ICRFp522B2096 whole embryo 5' read Protein similarity
  BI077490 cDNA clone IMAGE:5003869 tumor, biopsy sample 5' read Protein similarity
  BG807355 cDNA clone (no-name) neural retina
  BF577437 cDNA clone IMAGE:4206666 colon 5' read
  AA510164 cDNA clone IMAGE:862970 mammary gland 5' read
  AI614030 cDNA clone IMAGE:862970 mammary gland 5' read
  AA511056 cDNA clone IMAGE:891434 mammary gland 5' read
  AW321998 cDNA clone IMAGE:2609857 infiltrating ductal carcinoma 3' read Polyadenylation signal
  AI428423 cDNA clone IMAGE:553880 embryo 3' read Polyadenylation signal