Computational Discovery of Overlapping Transcriptional Units in the Human & Mouse Genomes

Candidate UniGene cluster:UniGene Cluster Mm.534
Description:insulin-like growth factor binding protein 7
Best-Of-UniGene (BOU) SequenceNM_008048
Genomic Coordiantes Displayed:Bases 334000 to 411000 of contig GA_x5J8B7W5D7G
BOU Orientation Along Contig:LEFT-TO-RIGHT with respect to contig
Link to JPEG of genomic mappingMm.534.jpeg
Best sense EST/protein match:NM_008048 matched ref|NP_032074.1| (NM_008048) insulin-like growth factor binding protein 7 [Mus (E = e-118)
Best antisense EST/protein match:AA270451 matched ref|NP_000929.1| (NM_000938) DNA directed RNA polymerase II polypeptide B; DNA (E = e-127)


This page provides information on exon-intron structure, mouse-human homologies, polyA signals & locations, and protein homologies of ESTs from directionally-cloned libraries that are members of a UniGene cluster that is a candidate for containing ESTs derived from distinct, overlapping sense & antisense transcripts.
The upper portion of the graph is reserved for the exon-intron mappings of ESTs oriented consistently with the Best-Of-UniGene (BOU) sequence (in gold). The lower portion of the graph is reserved for the exon-intron mappings of ESTs oriented opposite the BOU sequence (in white). Dividing these portions are the exon-intron mapping of the BOU sequence itself (in blue and green). Immedietely below the BOU are HUMMUS-defined streches of sequences highly conserved between mouse and human. The height of each bar is reflective of the % identity of human-mouse homology over a 100 base-pair window centered at a given base. At the left of the graph, the GenBank accession number of the BOU or EST sequence represented along that Y-axis position is listed, along with the UniLib identification number of the library from which that EST was derived.Below the graph, the GenBank accession numbers of each of the sense & antisense ESTs are provided, along with information on which have polyA signals and protein homologies, as determined by the NCBI.

Below are listed the same set of ESTs as is depicted above, with information of read direction, tissue type, protein similarity (P), and poly-adenylation signal (A).

ANTISENSE ESTs
  BE572376 cDNA clone IMAGE:3603506 infiltrating ductal carcinoma 5' read Protein similarity
  BG797408 cDNA clone (no-name) pancreas 3' read Polyadenylation signal
  BF012971 cDNA clone IMAGE:3655063 type b spermatogonia, pooled from multiple mice 5' read Protein similarityPolyadenylation signal
  AA178762 cDNA clone IMAGE:621558 spleen 5' read 0.5 kbProtein similarityPolyadenylation signal
  BM125483 cDNA clone (no-name) 3' read
  BI790460 cDNA clone (no-name) 3' read Protein similarity
  BF453351 cDNA clone IMAGE:3822140 spleen 5' read Protein similarity
  BE446892 cDNA clone IMAGE:3330415 spleen 3' read Protein similarity
  BF453346 cDNA clone IMAGE:3822128 spleen 5' read Protein similarity
  AA174610 cDNA clone IMAGE:620878 spleen 5' read Protein similarity
  BF142351 cDNA clone IMAGE:4022615 tumor, metastatic to mammary 5' read Polyadenylation signal
  BE692422 cDNA clone IMAGE:3416412 spleen 3' read Protein similarity
  BE446893 cDNA clone IMAGE:3330421 spleen 3' read Protein similarityPolyadenylation signal
  AA184095 cDNA clone IMAGE:621868 spleen 5' read Protein similarity
  BI790717 cDNA clone (no-name) 5' read Protein similarityPolyadenylation signal
  BM125713 cDNA clone (no-name) 5' read Polyadenylation signal
  BE850065 cDNA clone IMAGE:3416412 spleen 5' read Protein similarity
  AI322720 cDNA clone IMAGE:598619 spleen 5' read Protein similarity
  AA161899 cDNA clone IMAGE:598619 spleen 5' read Protein similarity
  AI153820 cDNA clone IMAGE:1449195 mammary gland 5' read
  AA982051 cDNA clone IMAGE:1348945 mammary gland 5' read Protein similarity
  AA980599 cDNA clone IMAGE:1349474 mammary gland 5' read Protein similarity
  AA672006 cDNA clone IMAGE:963751 mammary gland 5' read Protein similarity
  AW907701 cDNA clone IMAGE:3158185 infiltrating ductal carcinoma 3' read Protein similarityPolyadenylation signal
  AW212834 cDNA clone IMAGE:2647684 tumor, biopsy sample 3' read Protein similarityPolyadenylation signal
  BF662640 cDNA clone IMAGE:3823015 spleen 3' read Protein similarityPolyadenylation signal
  BF227961 cDNA clone IMAGE:3671302 tumor, gross tissue 3' read Protein similarityPolyadenylation signal
  AV222364 cDNA clone 3732422C19 embryonic body below diaphragm region
  BG075851 cDNA clone H3152F02 3' read Protein similarityPolyadenylation signal
  AW322220 cDNA clone IMAGE:2646216 spontaneous tumor, metastatic to mammary. stem cell origin. 3' read Protein similarityPolyadenylation signal
  AW557402 cDNA clone L0281D07 3' read Protein similarityPolyadenylation signal
  BG095339 cDNA clone IMAGE:4001624 spleen 5' read Protein similarity
  AW319562 cDNA clone IMAGE:2352712 kidney 3' read Protein similarityPolyadenylation signal
  AV287747 cDNA clone 5031439J16 ovary and uterus
  AW260260 cDNA clone IMAGE:2301071 kidney 3' read Protein similarity
  BE570509 cDNA clone IMAGE:3602718 infiltrating ductal carcinoma 5' read Protein similarity
  BE292553 cDNA clone IMAGE:3158185 infiltrating ductal carcinoma 3' read Protein similarityPolyadenylation signal
  BF660599 cDNA clone IMAGE:3823015 spleen 5' read Protein similarity
  AA754963 cDNA clone IMAGE:1194965 mammary gland 5' read Protein similarity
  AA213265 cDNA clone IMAGE:677492 liver 5' read Protein similarity
  AA260307 cDNA clone IMAGE:746971 embryo 5' read Protein similarity
  AA968205 cDNA clone IMAGE:1617924 hypothalamus 5' read Protein similarity
  AA270451 cDNA clone IMAGE:736489 embryo 5' read Protein similarity
  AA881136 cDNA clone IMAGE:1314980 mammary gland 5' read Protein similarity
  BI441162 cDNA clone (no-name) 5' read Protein similarity
  BG798788 cDNA clone (no-name) pancreas 5' read Protein similarity
  BI250037 cDNA clone IMAGE:5150925 tumor, gross tissue 5' read Protein similarity
  BF159850 cDNA clone IMAGE:3983234 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  BF124129 cDNA clone IMAGE:4024062 tumor, gross tissue 5' read Protein similarity
  BI691068 cDNA clone IMAGE:5345579 infiltrating ductal carcinoma 5' read Protein similarity
  AA793173 cDNA clone IMAGE:1069297 mammary gland 5' read Protein similarity
  BG917697 cDNA clone IMAGE:4949984 infiltrating ductal carcinoma 5' read Protein similarity
  BG866429 cDNA clone IMAGE:4911329 salivary gland 5' read Protein similarity
  BF117502 cDNA clone IMAGE:3671302 tumor, gross tissue 5' read Protein similarity
  BI647937 cDNA clone IMAGE:5316460 tumor, gross tissue 5' read Protein similarity
  BI666459 cDNA clone IMAGE:5322536 infiltrating ductal carcinoma 5' read Protein similarity
  BI078159 cDNA clone IMAGE:5004379 tumor, biopsy sample 5' read Protein similarity
  BF534635 cDNA clone IMAGE:4187749 salivary gland 5' read Protein similarity
  BE304326 cDNA clone IMAGE:3158185 infiltrating ductal carcinoma 5' read Protein similarity
  AW911663 cDNA clone IMAGE:3158185 infiltrating ductal carcinoma 5' read Protein similarity
  BG088392 cDNA clone H3152F02 5' read Protein similarity
  AW318475 cDNA clone IMAGE:2352712 kidney 5' read Protein similarity
  AW258984 cDNA clone IMAGE:2301071 kidney 5' read Protein similarity
  BF454584 cDNA clone IMAGE:3810291 salivary gland 5' read Protein similarity
  BI109121 cDNA clone IMAGE:5026936 tumor, gross tissue 5' read Protein similarity

SENSE ESTs

  BG270445 cDNA clone (no-name) total pancreas 5' read Protein similarity
  AI099240 cDNA clone IMAGE:872368 kidney 5' read Protein similarity
  AA106898 cDNA clone IMAGE:521957 muscle 5' read Protein similarity
  AA733431 cDNA clone IMAGE:1176994 colon 5' read Protein similarity
  AW260238 cDNA clone IMAGE:2301040 kidney 3' read Protein similarity
  AA109948 cDNA clone IMAGE:572536 kidney 5' read Protein similarity
  AW107026 cDNA clone IMAGE:2192681 kidney 5' read Protein similarity
  AA111624 cDNA clone IMAGE:572798 kidney 5' read Protein similarity
  AA275944 cDNA clone IMAGE:775857 kidney 5' read Protein similarity
  AA871242 cDNA clone IMAGE:1095987 bowel 5' read Protein similarity
  AA116648 cDNA clone IMAGE:579560 kidney 5' read Protein similarity
  AI747803 cDNA clone IMAGE:2064893 kidney 5' read Protein similarity
  AA123708 cDNA clone IMAGE:580072 kidney 5' read Protein similarity
  W45925 cDNA clone IMAGE:354748 embryo 5' read Protein similarity
  AA124037 cDNA clone IMAGE:578343 kidney 5' read Protein similarity
  AA276005 cDNA clone IMAGE:775849 kidney 5' read Protein similarity
  AI747910 cDNA clone IMAGE:2065015 kidney 5' read Protein similarity
  AA276066 cDNA clone IMAGE:776061 kidney 5' read Protein similarity
  AA276111 cDNA clone IMAGE:776135 kidney 5' read Protein similarity
  BI646146 cDNA clone IMAGE:5316494 tumor, gross tissue 5' read Protein similarity
  AI181124 cDNA clone IMAGE:1396207 mammary gland 5' read Protein similarity
  BG270464 cDNA clone (no-name) total pancreas 5' read Protein similarity
  AA276452 cDNA clone IMAGE:777092 kidney 5' read Protein similarity
  AI098256 cDNA clone IMAGE:872543 kidney 5' read Protein similarity
  AI098726 cDNA clone IMAGE:872271 kidney 5' read Protein similarity
  AI788557 cDNA clone IMAGE:1972058 kidney 3' read Protein similarity
  AA277973 cDNA clone IMAGE:766362 kidney 5' read Protein similarity
  AI314896 cDNA clone IMAGE:1921068 kidney 3' read Protein similarity
  BE376650 cDNA clone IMAGE:3584853 tumor, biopsy sample 5' read Protein similarity
  BE916301 cDNA clone IMAGE:3966833 tumor, biopsy sample 5' read Protein similarity
  AA286105 cDNA clone IMAGE:776389 kidney 5' read Protein similarity
  AA388499 cDNA clone IMAGE:790846 kidney 5' read Protein similarity
  AI789104 cDNA clone IMAGE:1972502 kidney 5' read Protein similarity
  AA469681 cDNA clone IMAGE:848881 kidney 5' read Protein similarity
  AA473084 cDNA clone IMAGE:803426 kidney 5' read Protein similarity
  AA473528 cDNA clone IMAGE:872062 kidney 5' read Protein similarity
  AA522109 cDNA clone IMAGE:903999 colon 5' read Protein similarity
  AI790558 cDNA clone IMAGE:2064905 kidney 3' read Protein similarity
  BE368344 cDNA clone IMAGE:3589249 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  AA617104 cDNA clone IMAGE:904471 colon 5' read Protein similarity
  AI790590 cDNA clone IMAGE:2065015 kidney 3' read Protein similarity
  AI987671 cDNA clone IMAGE:2182184 kidney 3' read Protein similarity
  AI647895 cDNA clone IMAGE:1971966 kidney 3' read Protein similarity
  AW318969 cDNA clone IMAGE:2394899 kidney 5' read Protein similarity
  AW261606 cDNA clone IMAGE:2331903 kidney 3' read Protein similarity
  AA275846 cDNA clone IMAGE:775634 kidney 5' read Protein similarity
  AI788779 cDNA clone IMAGE:1972755 kidney 3' read Protein similarity
  BG868819 cDNA clone IMAGE:4913609 salivary gland 5' read Protein similarity
  BE368345 cDNA clone IMAGE:3589297 spontaneous tumor, metastatic to mammary. stem cell origin. 5' read Protein similarity
  BG143312 cDNA clone (no-name) total pancreas 3' read Protein similarity
  AI648084 cDNA clone IMAGE:1971625 kidney 3' read Protein similarity
  AW107977 cDNA clone IMAGE:2192681 kidney 3' read Protein similarity
  AA575207 cDNA clone IMAGE:875874 mammary gland 5' read Protein similarity
  AA733345 cDNA clone IMAGE:1176799 colon 5' read Protein similarity
  BI101406 cDNA clone IMAGE:5042513 kidney 5' read Protein similarity
  AA397120 cDNA clone IMAGE:693312 liver 5' read Protein similarity
  AW320069 cDNA clone IMAGE:2395307 kidney 3' read Protein similarity
  BG143330 cDNA clone (no-name) total pancreas 3' read Protein similarityPolyadenylation signal
  AA823686 cDNA clone IMAGE:1245955 mammary gland 5' read Protein similarity
  AI414931 cDNA clone IMAGE:354748 embryo 3' read Protein similarityPolyadenylation signal
  BE447719 cDNA clone IMAGE:3329667 spleen 5' read Protein similarity
  AI020295 cDNA clone IMAGE:1367150 macrophage 5' read Protein similarity
  AA986314 cDNA clone IMAGE:1431862 kidney 3' read Protein similarityPolyadenylation signal
  BE447152 cDNA clone IMAGE:3331736 spleen 3' read Protein similarityPolyadenylation signal
  BE447439 cDNA clone IMAGE:3329667 spleen 3' read Protein similarityPolyadenylation signal
  AA137854 cDNA clone IMAGE:580535 kidney 5' read Protein similarity
  AA672841 cDNA clone IMAGE:1179738 mammary gland 5' read Protein similarity
  AA177694 cDNA clone IMAGE:622868 spleen 5' read Protein similarity
  AI118130 cDNA clone IMAGE:1482223 liver 3' read Protein similarityPolyadenylation signal
  Z31332 cDNA clone (no-name) testis Protein similarity
  W77044 cDNA clone IMAGE:400220 embryo 5' read Protein similarity
  BI715840 cDNA clone (no-name) 5' read Protein similarity
  AI157059 cDNA clone IMAGE:1434827 uterus 5' read Protein similarity
  AW319820 cDNA clone IMAGE:2394899 kidney 3' read Protein similarity
  AW210463 cDNA clone IMAGE:2270313 liver 3' read Protein similarity
  AW111590 cDNA clone MT3681 liver 3' read Protein similarity
  AA155486 cDNA clone IMAGE:598340 spleen 5' read Protein similarityPolyadenylation signal
  AA174835 cDNA clone IMAGE:616592 spleen 5' read Protein similarity
  AA106791 cDNA clone IMAGE:522074 muscle 5' read Protein similarity
  BE634409 cDNA clone IMAGE:3412268 spleen 5' read
  AV288739 cDNA clone 5033414K16 ovary and uterus
  BI555634 cDNA clone IMAGE:5292764 tumor, gross tissue 5' read Polyadenylation signal
  AV288903 cDNA clone 5033416C01 ovary and uterus
  AI467630 cDNA clone IMAGE:820833 mammary gland 3' read Polyadenylation signal
  AI552306 cDNA clone IMAGE:820833 mammary gland 5' read
  AA646670 cDNA clone IMAGE:820833 mammary gland 5' read
  AI386397 cDNA clone IMAGE:596384 spleen 5' read Protein similarity
  AI325972 cDNA clone IMAGE:596384 spleen 3' read Protein similarity
  AA138866 cDNA clone IMAGE:596384 spleen 5' read Protein similarity
  AA462257 cDNA clone IMAGE:850920 mammary gland 5' read
  AI481026 cDNA clone IMAGE:850920 mammary gland 3' read Protein similarity